(Q35543584)

English

Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension

scientific article published on 19 August 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

1 reference

based on heuristic

inferred from title

Johannes-Peter Stasch

8

object named as

Johannes-Peter Stasch

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Marc Chester

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Gregory Seedorf

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Pierre Tourneux

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Jason Gien

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Nancy Tseng

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Theresa Grover

6

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Jason Wright

7

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Steven H Abman

9

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

publication date

19 August 2011

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

301

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

L755-64

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Cinaciguat, a soluble guanylate cyclase activator, causes potent and sustained pulmonary vasodilation in the ovine fetus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

NO- and haem-independent activation of soluble guanylyl cyclase: molecular basis and cardiovascular implications of a new pharmacological principle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

NO-independent regulatory site on soluble guanylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Pulmonary hypertension alters soluble guanylate cyclase activity and expression in pulmonary arteries isolated from fetal lambs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Developmental changes in lung cGMP phosphodiesterase-5 activity, protein, and message

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

The cGMP phosphodiesterase inhibitor zaprinast enhances the effect of nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Cyclic guanosine monophosphate as a mediator of vasodilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Inhaled nitric oxide in persistent pulmonary hypertension of the newborn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

12 July 2018

Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Pulmonary vascular effects of nitric oxide-cGMP augmentation in a model of chronic pulmonary hypertension in fetal and neonatal sheep.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Identification of residues crucially involved in the binding of the heme moiety of soluble guanylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Soluble guanylate cyclase: an old therapeutic target re-visited.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Acute intrauterine pulmonary hypertension impairs endothelium-dependent vasodilation in the ovine fetus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Soluble guanylyl cyclase: structure and regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

Modulation of nitric oxide-dependent relaxation of pig tracheal smooth muscle by inhibitors of guanylyl cyclase and calcium activated potassium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213988

26 September 2018

The structural basis of persistent pulmonary hypertension of the newborn infant

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of intracellular Ca2+ levels in cultured vascular smooth muscle cells. Reduction of Ca2+ by atriopeptin and 8-bromo-cyclic GMP is mediated by cyclic GMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturational changes in endothelium-derived relaxing factor activity of ovine pulmonary arteries in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-Dose Nitric Oxide Therapy for Persistent Pulmonary Hypertension of the Newborn

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent pulmonary hypertension of the newborn infant

1 reference

https://pubmed.ncbi.nlm.nih.gov/21856817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPLUNG.00138.2010

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

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