(Q35285752)

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Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

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8 February 2020

Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes (English)

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8 February 2020

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Carlos J Miranda

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8 February 2020

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Fred H Gage

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8 February 2020

author name string

Mark E Hester

1

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8 February 2020

Matthew J Murtha

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8 February 2020

SungWon Song

3

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8 February 2020

Meghan Rao

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8 February 2020

Kathrin Meyer

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8 February 2020

Jinbin Tian

7

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8 February 2020

Gabriella Boulting

8

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8 February 2020

David V Schaffer

9

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8 February 2020

Michael X Zhu

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8 February 2020

Samuel L Pfaff

11

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8 February 2020

Brian K Kaspar

13

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8 February 2020

publication date

19 July 2011

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8 February 2020

Molecular Therapy

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8 February 2020

19

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8 February 2020

10

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8 February 2020

1905-1912

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8 February 2020

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

1 reference

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12 July 2018

A functionally characterized test set of human induced pluripotent stem cells

1 reference

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12 July 2018

AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice

1 reference

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12 July 2018

Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord

1 reference

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12 July 2018

CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy

1 reference

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12 July 2018

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

1 reference

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12 July 2018

Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC.

1 reference

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12 July 2018

Generation of induced pluripotent stem cells from human cord blood.

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12 July 2018

Two factor reprogramming of human neural stem cells into pluripotency

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12 July 2018

Direct reprogramming of human neural stem cells by OCT4.

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12 July 2018

Differentiation of spinal motor neurons from pluripotent human stem cells

1 reference

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12 July 2018

Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

1 reference

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12 July 2018

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

1 reference

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12 July 2018

Induced pluripotent stem cells from a spinal muscular atrophy patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy

1 reference

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12 July 2018

Neural differentiation of human embryonic stem cells

1 reference

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12 July 2018

Disease-specific induced pluripotent stem cells

1 reference

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12 July 2018

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

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12 July 2018

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

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12 July 2018

Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Functional neural development from human embryonic stem cells: accelerated synaptic activity via astrocyte coculture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Derivation of Motor Neurons from three Clonal Human Embryonic Stem Cell Lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Human motor neuron differentiation from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Functional properties of motoneurons derived from mouse embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Directed differentiation of embryonic stem cells into motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Transcriptional codes and the control of neuronal identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Transcriptional networks regulating neuronal identity in the developing spinal cord

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

12 July 2018

Specification of neuronal fates in the ventral neural tube

1 reference

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12 July 2018

Embryonic stem cell lines derived from human blastocysts

1 reference

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12 July 2018

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

1 reference

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12 July 2018

Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

1 reference

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12 July 2018

Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice

1 reference

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26 September 2018

Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy

1 reference

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26 September 2018

Generation of induced pluripotent stem cells from neural stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

26 September 2018

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188742

26 September 2018

A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity.

1 reference

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26 September 2018

Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells

1 reference

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26 September 2018

Specification of motoneurons from human embryonic stem cells.

1 reference

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26 September 2018

Motor neuron columnar fate imposed by sequential phases of Hox-c activity.

1 reference

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26 September 2018

LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21772256

12 December 2020

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10.1038/MT.2011.135

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8 February 2020

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Europe PubMed Central

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8 February 2020

1 reference

Europe PubMed Central

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8 February 2020

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