(Q35294913)

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Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formation

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 August 2017

Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formation (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Huntington's disease

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Dong Zhang

4

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author name string

Yanying Liu

1

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Europe PubMed Central

PubMed publication ID

7 August 2017

Yuanchao Xue

2

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Europe PubMed Central

PubMed publication ID

7 August 2017

Samantha Ridley

3

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Europe PubMed Central

PubMed publication ID

7 August 2017

Khosrow Rezvani

5

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

Xiang-Dong Fu

6

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7 August 2017

Hongmin Wang

7

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PubMed publication ID

7 August 2017

language of work or name

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publication date

2 October 2014

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Europe PubMed Central

PubMed publication ID

7 August 2017

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Europe PubMed Central

PubMed publication ID

7 August 2017

9

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Europe PubMed Central

PubMed publication ID

7 August 2017

10

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Europe PubMed Central

PubMed publication ID

7 August 2017

e109621

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Europe PubMed Central

PubMed publication ID

7 August 2017

copyright license

Creative Commons Attribution 4.0 International

2 October 2014

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April 2022 Public Data File from Crossref

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Modeling Huntington's disease with induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Prothymosin-α interacts with mutant huntingtin and suppresses its cytotoxicity in cell culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Modeling pathogenesis of Huntington's disease with inducible neuroprogenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Reprogramming Huntington monkey skin cells into pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Direct conversion of fibroblasts to functional neurons by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Effects of overexpression of huntingtin proteins on mitochondrial integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Disease-specific induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Huntingtin and its role in neuronal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Modeling Huntington's disease in cells, flies, and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Post-transcriptional regulation: the dawn of PTB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Differential loss of striatal projection neurons in Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

27 July 2018

Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Calretinin interacts with huntingtin and reduces mutant huntingtin-caused cytotoxicity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Immunohistological markers for staging neurogenesis in adult hippocampus.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Neuronal nuclear antigen (NeuN): a useful marker of neuronal immaturity in sudden unexplained perinatal death

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Brain-derived neurotrophic factor in Huntington disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109621

21 January 2018

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4183653

26 September 2018

Identifiers

10.1371/JOURNAL.PONE.0109621

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

2014PLoSO...9j9621L

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 August 2017

ResearchGate publication ID

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