(Q35312726)

7 August 2017

Thioredoxin reductase-2 is essential for keeping low levels of H(2)O(2) emission from isolated heart mitochondria (English)

1 reference

7 August 2017

Nazareno Paolocci

8

0 references

Iain McDonald

object named as

Iain McDonald

4

0 references

David Lloyd

object named as

David Lloyd

5

0 references

author name string

Brian A Stanley

1

1 reference

7 August 2017

Vidhya Sivakumaran

2

1 reference

7 August 2017

Sa Shi

3

1 reference

7 August 2017

Walter H Watson

6

1 reference

7 August 2017

Miguel A Aon

7

1 reference

7 August 2017

language of work or name

English

0 references

publication date

5 August 2011

1 reference

Journal of Biological Chemistry

7 August 2017

1 reference

7 August 2017

286

1 reference

7 August 2017

38

1 reference

7 August 2017

33669-33677

1 reference

describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3190932/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates

12 July 2018

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Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system

12 July 2018

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Redox-optimized ROS balance: a unifying hypothesis

12 July 2018

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The sites and topology of mitochondrial superoxide production

12 July 2018

1 reference

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Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

12 July 2018

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Potential therapeutic benefits of strategies directed to mitochondria.

12 July 2018

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Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands

12 July 2018

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Energetic performance is improved by specific activation of K+ fluxes through K(Ca) channels in heart mitochondria.

12 July 2018

1 reference

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Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects

12 July 2018

1 reference

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From mitochondrial dynamics to arrhythmias.

12 July 2018

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Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

12 July 2018

1 reference

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Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift

12 July 2018

1 reference

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Diabetes, oxidative stress, nitric oxide and mitochondria function.

12 July 2018

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Mitochondria and reactive oxygen species

12 July 2018

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Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function.

12 July 2018

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How mitochondria produce reactive oxygen species

12 July 2018

1 reference

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Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy.

12 July 2018

1 reference

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The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

12 July 2018

1 reference

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The redox environment in the mitochondrial intermembrane space is maintained separately from the cytosol and matrix

12 July 2018

1 reference

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ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

12 July 2018

1 reference

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A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

12 July 2018

1 reference

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Catalase takes part in rat liver mitochondria oxidative stress defense

12 July 2018

1 reference

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Sequential opening of mitochondrial ion channels as a function of glutathione redox thiol status.

12 July 2018

1 reference

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Mitochondria and cardioprotection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis

12 July 2018

1 reference

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Role of reactive oxygen species in myocardial remodeling.

12 July 2018

1 reference

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Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling

12 July 2018

1 reference

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Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

The mitochondrial origin of postischemic arrhythmias

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Mitochondrial metabolism of reactive oxygen species.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function

12 July 2018

1 reference

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Thioredoxin and its role in toxicology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Redox control of cell death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Peroxiredoxin, a novel family of peroxidases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat liver

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Inhibition of amino acid transport into lymphoid cells by the glutamine analog L-2-amino-4-oxo-5-chloropentanoate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Effect of glutathione depletion on sites and topology of superoxide and hydrogen peroxide production in mitochondria.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190932

Glutathione reductase in evolution

26 September 2018

1 reference

12 December 2020

Fluorometric quantitation of cellular and nonprotein thiols

1 reference

12 December 2020

Detection of catalase in rat heart mitochondria

1 reference

12 December 2020

1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity

1 reference

12 December 2020

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.284612

1 reference

7 August 2017

1 reference

7 August 2017

1 reference