(Q35322784)

7 August 2017

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title

Type 2 inflammation in asthma--present in most, absent in many (English)

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7 August 2017

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John V Fahy

1

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7 August 2017

publication date

1 January 2015

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Nature Reviews Immunology

7 August 2017

published in

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7 August 2017

volume

15

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7 August 2017

issue

1

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7 August 2017

page(s)

57-65

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https://scigraph.springernature.com/pub.10.1038/nri3786

7 August 2017

exact match

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cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells

12 July 2018

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Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Reslizumab for Poorly Controlled, Eosinophilic Asthma

12 July 2018

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Lebrikizumab treatment in adults with asthma

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

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12 July 2018

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12 July 2018

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12 July 2018

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A large-scale, consortium-based genomewide association study of asthma

12 July 2018

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Role of viral respiratory infections in asthma and asthma exacerbations

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells

12 July 2018

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Asthma and allergic inflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

12 July 2018

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T-helper type 2-driven inflammation defines major subphenotypes of asthma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Safety and tolerability of omalizumab

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Mepolizumab and exacerbations of refractory eosinophilic asthma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Cluster analysis and clinical asthma phenotypes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Oral corticosteroid-dependent asthma: a 30-year review

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Type 1/Type 2 immunity in infectious diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Inflammatory processes in bronchial asthma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Mepolizumab treatment in patients with severe eosinophilic asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Effects of an anti-TSLP antibody on allergen-induced asthmatic responses

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Dose-ranging study of lebrikizumab in asthmatic patients not receiving inhaled steroids

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Dupilumab in persistent asthma with elevated eosinophil levels

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Virus-induced eosinophil mediator release requires antigen-presenting and CD4+ T cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Airway inflammation and basement membrane tenascin in newly diagnosed atopic and nonatopic asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Treatment of allergic asthma with monoclonal anti-IgE antibody. rhuMAb-E25 Study Group.

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390063

Consistency of sputum eosinophilia in difficult-to-treat asthma: a 5-year follow-up study

26 September 2018

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The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects

31 March 2020

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31 March 2020

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Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial

31 March 2020

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Airway remodeling in asthma

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Binding of cynomolgus monkey IgE to a humanized anti-human IgE antibody and human high affinity IgE receptor

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31 March 2020

Identifiers

DOI

10.1038/NRI3786

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

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