(Q41779780)

English

A phase 1, randomized, placebo-controlled, dose-escalation study of an anti-IL-13 monoclonal antibody in healthy subjects and mild asthmatics

scientific article published on January 2013

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

A phase 1, randomized, placebo-controlled, dose-escalation study of an anti-IL-13 monoclonal antibody in healthy subjects and mild asthmatics (English)

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

0 references

0 references

author name string

Peter Hodsman

1

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Claire Ashman

2

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Anthony Cahn

3

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Erika De Boever

4

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Nicholas Locantore

5

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Adrian Serone

6

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Isabelle Pouliquen

7

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

language of work or name

0 references

publication date

1 January 2013

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

75

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

118-128

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

Lebrikizumab treatment in adults with asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Pharmacokinetics and pharmacodynamics of mepolizumab, an anti-interleukin-5 monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Subclinical phenotypes of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Cluster analysis and clinical asthma phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Exhaled nitric oxide in the diagnosis and management of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Measurement of IL-13-induced iNOS-derived gas phase nitric oxide in human bronchial epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

The reclassification of asthma based on subphenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Persistent effects induced by IL-13 in the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

IL-13 receptors and signaling pathways: An evolving web

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids. Asthma and Allergy Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Requirement for IL-13 independently of IL-4 in experimental asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Interleukin-13: central mediator of allergic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Eosinophils transcribe and translate messenger RNA for inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Sorting out the cytokines of asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

Endobronchial allergen challenge in asthma. Demonstration of cellular source of granulocyte macrophage colony-stimulating factor by in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

6 June 2018

IL-13 induced increases in nitrite levels are primarily driven by increases in inducible nitric oxide synthase as compared with effects on arginases in human primary bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Topical corticosteroid inhibits interleukin-4, -5 and -13 in nasal secretions following allergen challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Interleukin-13 in asthma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Age-related serum immunoglobulin E levels in healthy subjects and in patients with allergic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555051

18 August 2018

Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of high-dose fluticasone propionate and budesonide on lung function and asthma exacerbations in patients with severe asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of changes in mRNA for IL-5 in noninvasive scrapings of nasal epithelium taken from patients undergoing nasal allergen challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A detailed investigation of circulating IgE levels in a normal population

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of exhaled nitric oxide measurement with conventional tests in steroid-naive asthma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22616628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2012.04334.X

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

9 October 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41779780&oldid=1927799477"