(Q35324715)

7 August 2017

title

Protective role of PGC-1α in diabetic nephropathy is associated with the inhibition of ROS through mitochondrial dynamic remodeling (English)

1 reference

7 August 2017

1 reference

Kaifeng Guo

1

1 reference

7 August 2017

Junxi Lu

2

1 reference

7 August 2017

Yan Huang

3

1 reference

7 August 2017

Mian Wu

4

1 reference

7 August 2017

Lei Zhang

5

1 reference

7 August 2017

Haoyong Yu

6

1 reference

7 August 2017

Mingliang Zhang

7

1 reference

7 August 2017

Yuqian Bao

8

1 reference

7 August 2017

John Cijiang He

9

1 reference

7 August 2017

Haibing Chen

10

1 reference

7 August 2017

Weiping Jia

11

1 reference

7 August 2017

language of work or name

English

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publication date

8 April 2015

1 reference

7 August 2017

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7 August 2017

volume

10

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7 August 2017

issue

4

1 reference

7 August 2017

page(s)

e0125176

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Creative Commons Attribution 4.0 International

7 August 2017

copyright license

start time

8 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4390193/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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12 July 2018

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Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells

12 July 2018

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Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes

12 July 2018

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Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice

12 July 2018

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12 July 2018

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Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction

12 July 2018

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12 July 2018

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Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

12 July 2018

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High-fat diet induces an initial adaptation of mitochondrial bioenergetics in the kidney despite evident oxidative stress and mitochondrial ROS production

12 July 2018

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12 July 2018

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Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial reactive oxygen species pathway mediated by peroxisome proliferator-activated receptor gamma coactivator 1alpha

12 July 2018

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Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility

12 July 2018

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High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells

12 July 2018

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PGC-1alpha is a key regulator of glucose-induced proliferation and migration in vascular smooth muscle cells

12 July 2018

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Oxidative stress as a major culprit in kidney disease in diabetes

12 July 2018

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Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

12 July 2018

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Diabetes-induced alterations in renal medullary microcirculation and metabolism.

12 July 2018

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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

12 July 2018

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Metabolic control through the PGC-1 family of transcription coactivators

12 July 2018

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12 July 2018

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12 July 2018

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PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells

12 July 2018

1 reference

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Free fatty acids increase PGC-1alpha expression in isolated rat islets.

12 July 2018

1 reference

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Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.

12 July 2018

1 reference

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Mitochondrial morphology is dynamic and varied

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Reactive oxygen species cause diabetes-induced decrease in renal oxygen tension.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Maternal pregestational BMI is associated with methylation of the PPARGC1A promoter in newborns.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4390193

Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25853493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0125176

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference