(Q35329248)

7 August 2017

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title

Cibenzoline. A review of its pharmacological properties and therapeutic potential in arrhythmias (English)

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7 August 2017

2

Brogden RN

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7 August 2017

D. W. Harron

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1379150

20 September 2022

D. Faulds

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1379150

20 September 2022

A. Fitton

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1379150

20 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1379150

20 September 2022

publication date

1 May 1992

1 reference

7 August 2017

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7 August 2017

43

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7 August 2017

5

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7 August 2017

734-759

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https://scigraph.springernature.com/pub.10.2165/00003495-199243050-00008

7 August 2017

0 references

cites work

Cibenzoline for treatment of ventricular arrhythmias: a double-blind placebo-controlled study

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12 December 2020

Pharmacokinetics of oral cibenzoline in arrhythmia patients.

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12 December 2020

Effects on rabbit nodal, atrial, ventricular and Purkinje cell potentials of a new antiarrhythmic drug, cibenzoline, which protects against action potential shortening in hypoxia

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12 December 2020

Relative and absolute bioavailability of cibenzoline capsules and tablets in healthy subjects

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12 December 2020

Inhibition of the myocardial Ca2+ inward current by the class 1 antiarrhythmic agent, cibenzoline

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12 December 2020

Cardiac effects of cibenzoline.

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12 December 2020

Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction

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12 December 2020

[Effects of cibenzoline on myocardial ischemia].

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12 December 2020

Cibenzoline-induced hypoglycemia.

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12 December 2020

Cardiac electrophysiological effects of cibenzoline in the conscious dog: plasma concentration-response relationships

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12 December 2020

Quantitation of cibenzoline in human plasma by gas chromatography-negative ion chemical-ionization mass spectrometry

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12 December 2020

Pharmacokinetics in man of a new antiarrhythmic drug, cibenzoline

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of intravenous cibenzoline in normal volunteers.

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12 December 2020

Bioavailability and kinetics of cibenzoline in patients with normal and impaired renal function

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12 December 2020

Effect of oral cibenzoline on steady-state digoxin concentrations in healthy volunteers

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12 December 2020

Crossover comparison of cibenzoline and quinidine in ambulatory patients with chronic ventricular arrhythmias

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12 December 2020

Loss of efficacy during long-term cifenline therapy: development of antiarrhythmic resistance?

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12 December 2020

Hemodynamic effects of a new antiarrhythmic agent: cibenzoline

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12 December 2020

Efficacy and safety of oral cibenzoline for ventricular arrhythmias

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12 December 2020

Antiarrhythmic use of cibenzoline, a new class 1 antiarrhythmic agent with class 3 and 4 properties, in patients with recurrent ventricular tachycardia

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12 December 2020

Cibenzoline plasma concentration and antiarrhythmic effect.

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12 December 2020

[Cardiogenic shock and major intraventricular block in treatment with cibenzoline]

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12 December 2020

Quantification of cibenzoline and its imidazole metabolite by high-performance liquid chromatography in human serum

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12 December 2020

Pharmacokinetics of cibenzoline after single and repetitive dosing in healthy volunteers

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12 December 2020

Randomized comparison of flecainide and cibenzoline in the conversion of atrial fibrillation

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12 December 2020

Effect of cibenzoline, a class I antiarrhythmic drug, on action potential in canine ventricular muscle

1 reference

12 December 2020

Radioimmunoassay for the new antiarrhythmic agent cibenzoline in human plasma

1 reference

12 December 2020

Clinical electrophysiology, efficacy and safety of chronic oral cibenzoline therapy in refractory ventricular tachycardia

1 reference

12 December 2020

Effects of cibenzoline, a novel antiarrhythmic drug, on action potential and transmembrane currents in frog atrial muscle

1 reference

12 December 2020

The electrophysiologic effects of oral cibenzoline

1 reference

12 December 2020

Evaluation of dosing interval and optimum dose of cibenzoline

1 reference

12 December 2020

Cardiac electrophysiological effects of cibenzoline by acute and chronic administration in the anesthetized dog.

1 reference

12 December 2020

Comparative study of cibenzoline and flecainide administered via an intravenous route in reducing auricular arrhythmia

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12 December 2020

Can we predict sudden cardiac death?

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12 December 2020

Class Ic antiarrhythmic drugs and myocardial ischaemia: study in the pig heart in situ

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12 December 2020

[Electrophysiologic effects of intravenous cibenzoline succinate, a new class I antiarrhythmic agent]

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12 December 2020

The disposition and metabolic fate of 14C-cibenzoline in man

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12 December 2020

Pharmacokinetic and pharmacodynamic modeling of cibenzoline plasma concentrations and antiarrhythmic effect.

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12 December 2020

The arrhythmogenicity of antiarrhythmic agents

1 reference

12 December 2020

Antiarrhythmic efficacy and hemodynamic effects of cibenzoline in patients with nonsustained ventricular tachycardia and left ventricular dysfunction

1 reference

12 December 2020

Antiarrhythmic Effects of Optical Isomers of Cibenzoline on Canine Ventricular Arrhythmias

1 reference

12 December 2020

Effect of renal impairment on the pharmacokinetics of cibenzoline.

1 reference

12 December 2020

Effect of food on cibenzoline bioavailability

1 reference

12 December 2020

Mechanisms of sudden cardiac death

1 reference

12 December 2020

Single-dose pharmacokinetics and dose proportionality of oral cibenzoline.

1 reference

12 December 2020

Hypoglycaemia induced by cibenzoline

1 reference

12 December 2020

Pharmacokinetics of cibenzoline in patients with renal impairment

1 reference

12 December 2020

[Cardiogenic shock resistant to sodium lactate with high-dose of cibenzoline]

1 reference

12 December 2020

The efficacy of cibenzoline in preventing PES induction of ventricular tachycardia in the dog

1 reference

12 December 2020

Characterization of the class I antiarrhythmic activity of cibenzoline succinate in guinea pig papillary muscle.

1 reference

12 December 2020

The effect of cibenzoline on myocardial damages in dogs

1 reference

12 December 2020

QT-interval prolonging drugs: mechanisms and clinical relevance of their arrhythmogenic hazards

1 reference

12 December 2020

Age and cibenzoline disposition

1 reference

12 December 2020

Long-term antiarrhythmic therapy with cibenzoline

1 reference

12 December 2020

Cibenzoline for high-frequency ventricular arrhythmias: a short-term comparison with quinidine and a long-term follow-up

1 reference

12 December 2020

Cifenline in the short-term treatment of patients with ventricular premature complexes: a double-blind placebo-controlled study.

1 reference

12 December 2020

A comparison of antiarrhythmic drugs for the suppression of ventricular ectopic depolarizations: A meta-analysis

1 reference

12 December 2020

Clinical efficacy and electrophysiologic effects of cibenzoline therapy in patients with ventricular arrhythmias.

1 reference

12 December 2020

Hypoglycemia caused by cibenzoline. Apropos of a new case

1 reference

12 December 2020

The efficacy of cibenzoline and propafenone against inducible sustained and nonsustained ventricular tachycardias in conscious dogs with isolated chronic right ventricular infarction: a comparative study with procainamide

1 reference

12 December 2020

Comparison of Anticholinergic Effects of Cibenzoline, Disopyramide, and Atropine

1 reference

12 December 2020

Cibenzoline and hypoglycaemia

1 reference

12 December 2020

Comparative efficacy and safety of oral cibenzoline and quinidine in ventricular arrhythmias: a randomized crossover study

1 reference

12 December 2020

A nonradioactive iothalamate method for measuring glomerular filtration rate and its use to study the renal handling of cibenzoline

1 reference

12 December 2020

[Long-term prevention of the recurrence of auricular fibrillation using cibenzoline. Multicenter study apropos of 89 case reports]

1 reference

12 December 2020

Pharmacological mapping of regional effects in the rabbit heart of some new antiarrhythmic drugs

1 reference

12 December 2020

Visual compatibility of cibenzoline succinate with commonly used acute-care medications

1 reference

12 December 2020

Effect of congestive heart failure on the pharmacokinetics of cibenzoline

1 reference

12 December 2020

Use of Ringer lactate in cibenzoline poisoning

1 reference

12 December 2020

Acute, single, intravenous doses of cibenzoline: an evaluation of safety, tolerance, and hemodynamic effects

1 reference

12 December 2020

Determination of cibenzoline in plasma and urine by high-performance liquid chromatography

1 reference

12 December 2020

Antiarrhythmic effects of cibenzoline

1 reference

12 December 2020

Comparison of Ca2+ channel inhibitory effects of cibenzoline with verapamil on guinea-pig heart.

1 reference

12 December 2020

Haemodynamic effects of intravenous cibenzoline in patients with coronary heart disease.

1 reference

12 December 2020

Ventricular and atrial electrophysiological effects of a IC antiarrhythmic drug, cibenzoline, in the innervated dog heart. Role of sodium and calcium channels

1 reference

12 December 2020

Electrophysiological study of cibenzoline in voltage-clamped rabbit sinoatrial node preparations

1 reference

12 December 2020

Biotransformation of cibenzoline to 2-(2,2-diphenylcyclopropyl)-1H-imidazole

1 reference

12 December 2020

Cibenzoline for symptomatic ventricular arrhythmias: a prospective, randomized, double-blind, placebo controlled trial and a long term open label study

1 reference

12 December 2020

Electrophysiologic effects and efficacy of cibenzoline on stimulation-induced atrial fibrillation and flutter and implications for treatment of paroxysmal atrial fibrillation

1 reference

12 December 2020

Therapeutic effectiveness and plasma levels of single or combination use of class I antiarrhythmic agents for ventricular arrhythmias

1 reference

12 December 2020

Hypoglycemia induced by cibenzoline in the elderly

1 reference

12 December 2020

Electrophysiologic effects of cibenzoline in humans related to dose and plasma concentration

1 reference

12 December 2020

Electrophysiologic effects, antiarrhythmic activity and pharmacokinetics of cibenzoline studied with programmed stimulation of the heart in patients with supraventricular reentrant tachycardias.

1 reference

12 December 2020

Frequency- and time-dependent depression of ventricular distal conduction by two novel antiarrhythmic drugs, cibenzoline and flecainide

1 reference

12 December 2020

Effects of Intravenous Cibenzoline on Ventricular Vulnerability and Electrophysiology in Patients with Sustained Ventricular Tachycardia in Comparison to a Control Group

1 reference

12 December 2020

10.2165/00003495-199243050-00008

Identifiers

DOI

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Dimensions Publication ID

7 August 2017

0 references

1 reference