(Q35351777)

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Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-

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Europe PubMed Central

PubMed publication ID

7 August 2017

Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal- (English)

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Europe PubMed Central

PubMed publication ID

7 August 2017

non-small-cell lung carcinoma

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inferred from title

1

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Yong-Sung Juhnn

2

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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24 February 2015

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Europe PubMed Central

PubMed publication ID

7 August 2017

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

290

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

15

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

9604-9613

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer

1 reference

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12 July 2018

MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer

1 reference

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12 July 2018

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

1 reference

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12 July 2018

cAMP signaling in subcellular compartments

1 reference

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cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells

1 reference

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12 July 2018

USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation

1 reference

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12 July 2018

The short isoform of the ubiquitin ligase NEDD4L is a CREB target gene in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics

1 reference

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12 July 2018

Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

PKA: lessons learned after twenty years

1 reference

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12 July 2018

Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells.

1 reference

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12 July 2018

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

1 reference

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12 July 2018

Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling

1 reference

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12 July 2018

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

1 reference

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Developing histone deacetylase inhibitors as anti-cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Heterotrimeric stimulatory GTP-binding proteins inhibit cisplatin-induced apoptosis by increasing X-linked inhibitor of apoptosis protein expression in cervical cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Mechanisms involved in 3',5'-cyclic adenosine monophosphate-mediated inhibition of the ubiquitin-proteasome system in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Recent progress in the biology and physiology of sirtuins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Stimulatory heterotrimeric GTP-binding protein augments cisplatin-induced apoptosis by upregulating Bak expression in human lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

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1 reference

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12 July 2018

Functions of site-specific histone acetylation and deacetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

12 July 2018

Specificity in the cAMP/PKA signaling pathway. Differential expression,regulation, and subcellular localization of subunits of PKA.

1 reference

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12 July 2018

Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

1 reference

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Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit

1 reference

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1 reference

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1 reference

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1 reference

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26 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392263

26 September 2018

Molecular Pathogenesis of Lung Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713071

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713071

12 December 2020

based on heuristic

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Recent clinical advances in lung cancer management

1 reference

https://pubmed.ncbi.nlm.nih.gov/25713071

12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.M114.633198

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

release_s4uj345o4rhlnfps6fhpjl64tm

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https://api.fatcat.wiki/v0/release/s4uj345o4rhlnfps6fhpjl64tm

24 November 2022

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25713071%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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