(Q35353325)

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High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25332350%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25332350%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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trypanosomiasis

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African trypanosomiasis

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natural product

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1

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21 February 2020

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21 February 2020

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21 February 2020

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21 February 2020

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21 February 2020

Santiago Castanys

14

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21 February 2020

Luis Miguel Ruiz-Pérez

15

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21 February 2020

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21 February 2020

Francisco Gamarro

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21 February 2020

Dolores Gonzalez-Pacanowska

18

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21 February 2020

author name string

G Pérez-Moreno

2

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21 February 2020

R García-Hernández

3

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21 February 2020

C Cordon-Obras

4

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21 February 2020

J Martín

5

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21 February 2020

L Rodríguez

7

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21 February 2020

N de Pedro

8

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21 February 2020

V Gómez-Pérez

9

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21 February 2020

F Vicente

13

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21 February 2020

publication date

20 October 2014

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21 February 2020

Journal of Biomolecular Screening

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21 February 2020

20

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21 February 2020

1

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21 February 2020

82-91

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21 February 2020

Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness).

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

Management of trypanosomiasis and leishmaniasis

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

High-throughput screening: update on practices and success

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

The evolving role of natural products in drug discovery

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

Natural compounds: leads or ideas? Bioinspired molecules for drug discovery

1 reference

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21 January 2018

Natural products as sources of new drugs over the 30 years from 1981 to 2010

1 reference

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21 January 2018

Natural product based leads to fight against leishmaniasis

1 reference

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21 January 2018

Axenic culture of African trypanosome bloodstream forms

1 reference

https://api.crossref.org/works/10.1177%2F1087057114555846

21 January 2018

An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds

1 reference

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21 January 2018

Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening

1 reference

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21 January 2018

Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay

1 reference

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21 January 2018

In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences

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21 January 2018

Pharmacology of diminazene: a review

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21 January 2018

The development of drugs for treatment of sleeping sickness: a historical review

1 reference

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21 January 2018

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis

1 reference

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21 January 2018

New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi

1 reference

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21 January 2018

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs

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21 January 2018

In vitro and in vivo activities of echinomycin against clinical isolates of Staphylococcus aureus

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Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis

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Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases.

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21 January 2018

Upregulation of heat shock protein 27 confers resistance to actinomycin D-induced apoptosis in cancer cells

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21 January 2018

Nucleolar accumulation of RNA binding proteins induced by Actinomycin D is functional in Trypanosoma cruzi and Leishmania mexicana but not in T. brucei

1 reference

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21 January 2018

Trypanosoma cruzi: in vitro morphological alterations induced by actinomycin D.

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Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity

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Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites

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Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

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21 January 2018

Autophagy, bafilomycin and cell death: the "a-B-cs" of plecomacrolide-induced neuroprotection

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Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons

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Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death

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21 January 2018

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