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Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
title
Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
main subject
metformin
1 reference
based on heuristic
inferred from title
author
Alba Luengo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
Lucas B Sullivan
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
author name string
Matthew G Vander Heiden
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
publication date
24 October 2014
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
published in
BMC Biology
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
volume
12
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
page(s)
82
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
copyright license
Creative Commons Attribution 4.0 International
start time
24 October 2014
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
exact match
https://scigraph.springernature.com/pub.10.1186/s12915-014-0082-4
0 references
cites work
Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
LKB1 and AMPK and the cancer-metabolism link - ten years after
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Investigating metformin for cancer prevention and treatment: the end of the beginning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
12 July 2018
Metformin directly acts on mitochondria to alter cellular bioenergetics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
26 September 2018
Metformin suppresses intestinal polyp growth in ApcMin/+ mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4207883
retrieved
26 September 2018
Identifiers
DOI
10.1186/S12915-014-0082-4
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
Dimensions Publication ID
1000162666
0 references
PMCID
4207883
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PubMed ID
25347702
1 reference
stated in
Europe PubMed Central
PMCID
4207883
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25347702%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
ResearchGate publication ID
267730142
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