(Q35374908)

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Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo

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22 February 2020

Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo (English)

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22 February 2020

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22 February 2020

Robert S. Langer, Jr.

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Robert Langer

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22 February 2020

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Omar F Khan

1

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22 February 2020

Edmond W Zaia

2

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22 February 2020

Hao Yin

3

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22 February 2020

Roman L Bogorad

4

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22 February 2020

Jeisa M Pelet

5

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22 February 2020

Iris Zhuang

7

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22 February 2020

James E Dahlman

8

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22 February 2020

Daniel G Anderson

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22 February 2020

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publication date

29 October 2014

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22 February 2020

Angewandte Chemie International Edition

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22 February 2020

53

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22 February 2020

52

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22 February 2020

14397-14401

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25354018%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Copolymer of poly(ethylene glycol) and poly(L-lysine) grafting polyethylenimine through a reducible disulfide linkage for siRNA delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Can nanomedicines kill cancer stem cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Glycine-terminated dendritic amphiphiles for nonviral gene delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

The effect of nanoparticle size, shape, and surface chemistry on biological systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Intrinsically fluorescent PAMAM dendrimer as gene carrier and nanoprobe for nucleic acids delivery: bioimaging and transfection study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Multifunctional triblock Nanocarrier (PAMAM-PEG-PLL) for the efficient intracellular siRNA delivery and gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Lipid-like materials for low-dose, in vivo gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Cooperative nanomaterial system to sensitize, target, and treat tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Development of lipidoid-siRNA formulations for systemic delivery to the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Efficient delivery of siRNA using dendritic poly(L-lysine) for loss-of-function analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Distinct pathways of genomic progression to benign and malignant tumors of the liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Development and characterisation of chitosan nanoparticles for siRNA delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Biophysical and structural characterization of polyethylenimine-mediated siRNA delivery in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Tie-2 is expressed on thyroid follicular cells, is increased in goiter, and is regulated by thyrotropin through cyclic adenosine 3',5'-monophosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

RNA interference is mediated by 21- and 22-nucleotide RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Effects of apolipoproteins A-IV and A-I on the uptake of phospholipid liposomes by hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4785599

27 July 2018

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Safety and efficacy of RNAi therapy for transthyretin amyloidosis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Small RNA combination therapy for lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Hyperbranched polymeric "star vectors" for effective DNA or siRNA delivery

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Polypropylenimine dendrimer-induced gene expression changes: the effect of complexation with DNA, dendrimer generation and cell type.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201408221

21 January 2018

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ANIE.201408221

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25354018%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25354018%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25354018%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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