(Q35430964)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Ottavio Arancio

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Julio Pozueta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Roger Lefort

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Carol M Troy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Michael Shelanski

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

1 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

1939

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4398315/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease

12 July 2018

1 reference

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Aβ toxicity in Alzheimer's disease

12 July 2018

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Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

12 July 2018

1 reference

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Cystatin C protects neuronal cells from amyloid-beta-induced toxicity

12 July 2018

1 reference

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

12 July 2018

1 reference

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Relevance of abeta1-42 intrahippocampal injection as an animal model of inflamed Alzheimer's disease brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

12 July 2018

1 reference

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Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

A decade of modeling Alzheimer's disease in transgenic mice.

12 July 2018

1 reference

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Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: evidence for two forms of spine motility

12 July 2018

1 reference

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Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes

12 July 2018

1 reference

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Caspase cleavage of the amyloid precursor protein modulates amyloid β‐protein toxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

12 July 2018

1 reference

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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

12 July 2018

1 reference

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Changes in caspase expression in Alzheimer's disease: comparison with development and aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Defects in regulation of apoptosis in caspase-2-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Mechanisms of neuronal degeneration: a final common pathway?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase activation without apoptosis: insight into Aβ initiation of neurodegeneration.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Altered distribution of RhoA in Alzheimer's disease and AbetaPP overexpressing mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Local caspase activity directs engulfment of dendrites during pruning.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

The association between RhoB and caspase-2: changes with lovastatin-induced apoptosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Dendrite and dendritic spine alterations in Alzheimer models

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Neuronal DNA damage correlates with overexpression of interleukin-1beta converting enzyme in APPV717F mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Quantitative synaptic alterations in the human neocortex during normal aging

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Synaptic and neuritic alterations during the progression of Alzheimer's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4398315

Caspase-2 mediates neuronal cell death induced by beta-amyloid

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23748737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23748737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS2927

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

23748737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23748737%20AND%20SRC:MED&resulttype=core&format=json