(Q53315554)

13 May 2018

title

Caspase activation without apoptosis: insight into Aβ initiation of neurodegeneration. (English)

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13 May 2018

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1

Bradley T Hyman

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13 May 2018

language of work or name

English

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publication date

1 January 2011

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13 May 2018

published in

Nature Neuroscience

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13 May 2018

volume

14

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13 May 2018

issue

1

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13 May 2018

page(s)

5-6

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/nn0111-5

exact match

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cites work

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

1 reference

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

21 January 2018

1 reference

Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.

21 January 2018

1 reference

Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease

21 January 2018

1 reference

Mechanisms of neuronal death in disease: defining the models and the players.

21 January 2018

1 reference

Caspase activation precedes and leads to tangles

21 January 2018

1 reference

Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy

21 January 2018

1 reference

APP processing and synaptic function

21 January 2018

1 reference

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

1 reference

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

21 January 2018

1 reference

Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

21 January 2018

1 reference

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

21 January 2018

1 reference

Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21187847

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21187847

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN0111-5

1 reference

13 May 2018

1 reference

13 May 2018