(Q35441529)

8 August 2017

title

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer (English)

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8 August 2017

Carmine Stolfi

1

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Flavio Caprioli

object named as

Flavio Caprioli

11

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author name string

Angelamaria Rizzo

2

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8 August 2017

Eleonora Franzè

3

1 reference

8 August 2017

Angela Rotondi

4

1 reference

8 August 2017

Massimo Claudio Fantini

5

1 reference

8 August 2017

Massimiliano Sarra

6

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8 August 2017

Roberta Caruso

7

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8 August 2017

Ivan Monteleone

8

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8 August 2017

Pierpaolo Sileri

9

1 reference

8 August 2017

Luana Franceschilli

10

1 reference

8 August 2017

Stefano Ferrero

12

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8 August 2017

Thomas T MacDonald

13

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8 August 2017

Francesco Pallone

14

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8 August 2017

Giovanni Monteleone

15

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8 August 2017

language of work or name

English

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publication date

10 October 2011

1 reference

Journal of Experimental Medicine

8 August 2017

published in

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8 August 2017

volume

208

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8 August 2017

issue

11

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8 August 2017

page(s)

2279-2290

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Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

8 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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Up for Mischief? IL-17/Th17 in the tumour microenvironment

12 July 2018

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Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells

12 July 2018

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Inflammation and colon cancer

12 July 2018

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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

12 July 2018

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

12 July 2018

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Interleukin-21 as a new therapeutic target for immune-mediated diseases

12 July 2018

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IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

12 July 2018

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Regulation and function of NF-kappaB transcription factors in the immune system

12 July 2018

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Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease

12 July 2018

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

12 July 2018

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Cancer-related inflammation

12 July 2018

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The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer

12 July 2018

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Signaling molecules: the pathogenic role of the IL-6/STAT-3 trans signaling pathway in intestinal inflammation and in colonic cancer

12 July 2018

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Interleukin 21: combination strategies for cancer therapy

12 July 2018

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Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

12 July 2018

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Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study

12 July 2018

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

12 July 2018

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The IL-21 receptor augments Th2 effector function and alternative macrophage activation

12 July 2018

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Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease

12 July 2018

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

12 July 2018

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IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201207

A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate

12 July 2018

1 reference

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Regulation of gut inflammation and th17 cell response by interleukin-21.

12 July 2018

1 reference

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IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells.

26 September 2018

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Interleukin-21 gene transfection into mouse bladder cancer cells results in tumor rejection through the cytotoxic T lymphocyte response

26 September 2018

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The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.

26 September 2018

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In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.

26 September 2018

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CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice.

26 September 2018

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Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.

26 September 2018

1 reference

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IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma

26 September 2018

1 reference

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Safety and Clinical Effect of Subcutaneous Human Interleukin-21 in Patients with Metastatic Melanoma or Renal Cell Carcinoma: A Phase I Trial

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20111106

In vivo antitumor activity of interleukin 21 mediated by natural killer cells

21 January 2018

1 reference

12 December 2020

Expression of Foxp3 in non-small cell lung cancer patients is significantly higher in tumor tissues than in normal tissues, especially in tumors smaller than 30 mm

1 reference

12 December 2020

A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

1 reference

12 December 2020

Autocrine regulation of IL-21 production in human T lymphocytes

1 reference

12 December 2020

Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20111106

1 reference

8 August 2017

1 reference

8 August 2017

1 reference