(Q35472380)

8 August 2017

title

A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections (English)

1 reference

8 August 2017

1 reference

1 reference

Curtis J Pritzl

1

1 reference

8 August 2017

Young-Jin Seo

2

1 reference

8 August 2017

Chuan Xia

3

1 reference

8 August 2017

Madhuvanthi Vijayan

4

1 reference

8 August 2017

Zachary D Stokes

5

1 reference

8 August 2017

Bumsuk Hahm

6

1 reference

8 August 2017

language of work or name

English

0 references

publication date

25 March 2015

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8 August 2017

published in

Journal of Immunology

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8 August 2017

volume

194

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8 August 2017

issue

9

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8 August 2017

page(s)

4339-4349

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Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling

8 August 2017

cites work

1 reference

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Sphingosine analog AAL-R promotes activation of LCMV-infected dendritic cells

27 July 2018

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Ceramide synthases as potential targets for therapeutic intervention in human diseases

27 July 2018

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Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system

27 July 2018

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Persistent LCMV infection is controlled by blockade of type I interferon signaling

27 July 2018

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Blockade of chronic type I interferon signaling to control persistent LCMV infection

27 July 2018

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Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

27 July 2018

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Sphingosine analogue AAL-R increases TLR7-mediated dendritic cell responses via p38 and type I IFN signaling pathways

27 July 2018

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Profiling changes triggered during maturation of dendritic cells: a lipidomic approach

27 July 2018

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27 July 2018

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27 July 2018

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Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

27 July 2018

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Ceramide induces apoptosis via caspase-dependent and caspase-independent pathways in mesenchymal stem cells derived from human adipose tissue

27 July 2018

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Ceramide and ceramide 1-phosphate are negative regulators of TNF-α production induced by lipopolysaccharide

27 July 2018

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

27 July 2018

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Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory.

27 July 2018

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Hostile communication of measles virus with host innate immunity and dendritic cells

27 July 2018

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A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry.

27 July 2018

1 reference

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

27 July 2018

1 reference

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Interleukin-10 determines viral clearance or persistence in vivo

27 July 2018

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Resolution of a chronic viral infection after interleukin-10 receptor blockade

27 July 2018

1 reference

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Restoring function in exhausted CD8 T cells during chronic viral infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide, a target for antiretroviral therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Interplay of natural killer cells and their receptors with the adaptive immune response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Viral immunosuppression: disabling the guards

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide induces cell cycle arrest and upregulates p27kip in nasopharyngeal carcinoma cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Dual effect of ceramide on human endothelial cells: induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Generation of cellular immune responses to antigenic tumor peptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide inhibits antigen uptake and presentation by dendritic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide induces apoptosis in cultured mesencephalic neurons.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Role for ceramide in cell cycle arrest.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

CD28 signals through acidic sphingomyelinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

A Mediator Role of Ceramide in the Regulation of Neuroblastoma Neuro2a Cell Differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Dendritic cells initiate a two-stage mechanism for T lymphocyte proliferation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Modulation of cell growth and differentiation by ceramide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Sphingosine kinase 1 serves as a pro-viral factor by regulating viral RNA synthesis and nuclear export of viral ribonucleoprotein complex upon influenza virus infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Systemic ceramide accumulation leads to severe and varied pathological consequences.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide inhibits LPS-induced production of IL-5, IL-10, and IL-13 from mast cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Liposomal delivery of antigen to human dendritic cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Induction of oligodendrocyte apoptosis by C2-ceramide.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402267

Enhanced delivery of immunoliposomes to human dendritic cells by targeting the multilectin receptor DEC-205

26 September 2018

1 reference

12 December 2020

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

1 reference

12 December 2020

Ceramide induces apoptosis via CPP32 activation

1 reference

12 December 2020

Ceramide induces apoptosis in PC12 cells

1 reference

12 December 2020

Toll-like receptors: linking innate and adaptive immunity

1 reference

12 December 2020

Ceramide initiates NFkappaB-mediated caspase activation in neuronal apoptosis

1 reference

12 December 2020

Stress signals for apoptosis: ceramide and c-Jun kinase

1 reference

12 December 2020

4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses

1 reference

12 December 2020

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1402672

1 reference

8 August 2017

1 reference

8 August 2017

1 reference