(Q84068693)

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31 January 2020

title

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes (English)

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31 January 2020

2

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31 January 2020

12

Martin Krönke

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31 January 2020

author name string

Jasmin Herz

1

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31 January 2020

Hamid Kashkar

3

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31 January 2020

Michael Schramm

4

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31 January 2020

Elza Kuzmenkina

5

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31 January 2020

Erik Bos

6

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31 January 2020

Katja Wiegmann

7

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31 January 2020

Reinhard Wallich

8

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31 January 2020

Peter J Peters

9

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31 January 2020

Stefan Herzig

10

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31 January 2020

Elmon Schmelzer

11

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31 January 2020

Markus M Simon

13

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31 January 2020

Olaf Utermöhlen

14

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31 January 2020

publication date

14 June 2009

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31 January 2020

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31 January 2020

volume

10

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31 January 2020

page(s)

761-768

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31 January 2020

issue

7

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The ins and outs of sphingolipid synthesis

31 January 2020

cites work

1 reference

12 December 2020

Virus-induced delayed-type hypersensitivity reaction is sequentially mediated by CD8+ and CD4+ T lymphocytes

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12 December 2020

The T cell-specific serine proteinase TSP-1 is associated with cytoplasmic granules of cytolytic T lymphocytes

1 reference

12 December 2020

Mechanism of recovery from acute virus infection. I. Role of T lymphocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice.

1 reference

12 December 2020

Lateral diffusivity of lipid analogue excimeric probes in dimyristoylphosphatidylcholine bilayers

1 reference

12 December 2020

Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes

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12 December 2020

Sphingomyelinases: enzymology and membrane activity

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12 December 2020

Determination of frequency of T cells expressing the T cell-specific serine proteinase 1 (TSP-1) reveals two types of L3T4+ T lymphocytes

1 reference

12 December 2020

A new quantitative (two-photon extracellular polar-tracer imaging-based quantification (TEPIQ)) analysis for diameters of exocytic vesicles and its application to mouse pancreatic islets

1 reference

12 December 2020

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

1 reference

12 December 2020

Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4

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12 December 2020

Single granule pH cycling in antigen-induced mast cell secretion

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12 December 2020

Perforin dependence of natural killer cell-mediated tumor control in vivo

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12 December 2020

Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes

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12 December 2020

Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes

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12 December 2020

Acid sphingomyelinase is required for efficient phago-lysosomal fusion

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12 December 2020

Pyrene-labeled gangliosides: micelle formation in aqueous solution, lateral diffusion, and thermotropic behavior in phosphatidylcholine bilayers.

1 reference

12 December 2020

The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene

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12 December 2020

Surface tension induced by sphingomyelin to ceramide conversion in lipid membranes

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12 December 2020

Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane

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12 December 2020

Lipid traffic: floppy drives and a superhighway.

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12 December 2020

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

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12 December 2020

Phagosomal pH determination by dual fluorescence flow cytometry

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12 December 2020

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease

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12 December 2020

Ceramide-enriched membrane domains

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12 December 2020

Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?

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12 December 2020

Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology

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12 December 2020

Shouts, whispers and the kiss of death: directional secretion in T cells

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12 December 2020

Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism

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12 December 2020

An update of the enzymology and regulation of sphingomyelin metabolism

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12 December 2020

Resolution of fusion pore formation in a cell-attached patch

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12 December 2020

Formation of a central supramolecular activation cluster is not required for activation of naive CD8+ T cells

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12 December 2020

Elevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)

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12 December 2020

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

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12 December 2020

Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse.

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12 December 2020

The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts

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12 December 2020

Protein-Lipid Interplay in Fusion and Fission of Biological Membranes

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12 December 2020

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12 December 2020

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

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12 December 2020

The immunological synapse of CTL contains a secretory domain and membrane bridges.

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12 December 2020

Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin

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12 December 2020

The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells

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12 December 2020

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

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12 December 2020

Do CTL kill target cells by inducing apoptosis?

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12 December 2020

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

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12 December 2020

Secretory mechanisms in cell-mediated cytotoxicity

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12 December 2020

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

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12 December 2020

Biophysics of ceramide signaling: interaction with proteins and phase transition of membranes

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12 December 2020

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation

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12 December 2020

Identifiers

DOI

10.1038/NI.1757

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31 January 2020

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