(Q35499214)

English

Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

1 reference

ChEBI release 2020-05-28

object named as

Amaryllidaceae

1 reference

based on heuristic

inferred from title

Delphine Lamoral-Theys

1

object named as

Delphine Lamoral-Theys

0 references

Gwendoline Van Goietsenoven

3

object named as

Gwendoline Van Goietsenoven

0 references

Nathalie Wauthoz

object named as

Nathalie Wauthoz

6

0 references

Alessio Cimmino

object named as

Alessio Cimmino

4

0 references

object named as

Anna Andolfi

2

0 references

Alexander Kornienko

12

object named as

Alexander Kornienko

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Delphine Lamoral-Theys

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Gwendoline Van Goietsenoven

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Benjamin Le Calvé

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Véronique Mégalizzi

7

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Thierry Gras

8

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Céline Bruyère

9

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Jacques Dubois

10

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Véronique Mathieu

11

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Robert Kiss

13

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Antonio Evidente

14

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

0 references

publication date

1 October 2009

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

52

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

6244-6256

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids

1 reference

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12 July 2018

The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment

1 reference

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12 July 2018

Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design

1 reference

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12 July 2018

Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Amaryllidaceae isocarbostyril alkaloids and their derivatives as promising antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Videomicroscopic extraction of specific information on cell proliferation and migration in vitro

1 reference

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12 July 2018

Chemistry, biology, and medicinal potential of narciclasine and its congeners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells

1 reference

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12 July 2018

The microfilament system and malignancy

1 reference

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12 July 2018

The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity

1 reference

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12 July 2018

Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model

1 reference

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12 July 2018

CNS metastasis: an old problem in a new guise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Treatment of lycorine on SCID mice model with human APL cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Drug resistance in melanoma: new perspectives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Apoptosis and melanoma: how new insights are effecting the development of new therapies for melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Treatment options for brain metastases from melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Tracking of migrating cells under phase-contrast video microscopy with combined mean-shift processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Treatment of metastatic malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Caspase regulation in non-small cell lung cancer and its potential for therapeutic exploitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

(-)-Amarbellisine, a lycorine-type alkaloid from Amaryllis belladonna L. growing in Egypt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Cytoskeletal network in colon cancer: from genes to clinical application

1 reference

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12 July 2018

The actin cytoskeleton as a therapeutic target: state of the art and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Evaluation of the efficiency of chemotherapy in in vivo orthotopic models of human glioma cells with and without 1p19q deletions and in C6 rat orthotopic allografts serving for the evaluation of surgery combined with chemotherapy.

1 reference

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12 July 2018

Molecular biology of esophageal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

12 July 2018

Growth inhibition of human in vitro and mouse in vitro and in vivo mammary tumor models by retinoids in comparison with tamoxifen and the RU-486 anti-progestagen.

1 reference

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12 July 2018

Ascorbate system in plant development

1 reference

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12 July 2018

Narciclasine, a plant growth modulator, activates Rho and stress fibers in glioblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

26 September 2018

Lycorine induces apoptosis and down-regulation of Mcl-1 in human leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

26 September 2018

Ascorbic Acid as a factor controlling the development of cyanide-insensitive respiration

1 reference

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26 September 2018

Selective cytotoxicity of pancratistatin-related natural Amaryllidaceae alkaloids: evaluation of the activity of two new compounds

1 reference

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26 September 2018

Pancratistatin: a natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

26 September 2018

Effects of lycorine on HL-60 cells via arresting cell cycle and inducing apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

26 September 2018

Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205972

26 September 2018

Alkaloid biosynthesis and interconversions. Conversion of caranine to lycorine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19788245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Amaryllidaceae alkaloids. Absolute confuigurations diasteroisomeric methiodides in the lycorine-type alkaloids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19788245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM901031H

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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