(Q35523730)

8 August 2017

title

Optimization of propafenone analogues as antimalarial leads (English)

1 reference

8 August 2017

0 references

2

W Armand Guiguemde

1 reference

8 August 2017

Andrew S Lemoff

7

0 references

R. Kiplin Guy

series ordinal

10

object named as

R Kiplin Guy

1 reference

8 August 2017

3

Michele C Connelly

1 reference

8 August 2017

4

Fangyi Zhu

1 reference

8 August 2017

8

Joseph L Derisi

1 reference

8 August 2017

5

Martina S Sigal

1 reference

8 August 2017

David J Lowes

1

1 reference

8 August 2017

Julie A Clark

series ordinal

6

1 reference

8 August 2017

Emily B Wilson

series ordinal

9

1 reference

8 August 2017

language of work or name

English

0 references

publication date

10 October 2011

1 reference

Journal of Medicinal Chemistry

8 August 2017

published in

1 reference

8 August 2017

volume

54

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8 August 2017

issue

21

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8 August 2017

page(s)

7477-7485

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Artemisinin Resistance in Plasmodium falciparum Malaria

8 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Dual detection approach to a more accurate measure of relative purity in high-throughput characterization of compound collections

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

The role of fluorine in medicinal chemistry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

hERG potassium channels and cardiac arrhythmia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Drug resistance hampers our capacity to roll back malaria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

The global distribution of clinical episodes of Plasmodium falciparum malaria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Fluorine in medicinal chemistry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Identification and determination of phase I metabolites of propafenone in rat liver perfusate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Clinical pharmacology and beta-blocking efficacy of propafenone

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Effect of the antiarrhythmic agent propaphenone on cardiac conduction. clinical studies using bundle of his electrography

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Searching for new antimalarial therapeutics amongst known drugs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Human malaria parasites in continuous culture. 1976.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Parallel synthesis and antimalarial screening of a 4-aminoquinoline library

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

A subset of highly effective propafenone-type multidrug resistance modulators lacks effects on cardiac action potential and mechanical twitch parameters of rat papillary muscles

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Synthesis, Pharmacologic Activity, and Structure-Activity Relationships of a Series of Propafenone-Related Modulators of Multidrug Resistance

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208124

Propafenone interacts stereoselectively with beta 1- and beta 2-adrenergic receptors

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21955244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High throughput microsomal stability assay for insoluble compounds

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21955244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluorine in medicinal chemistry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21955244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM2005546

1 reference

8 August 2017

1 reference

8 August 2017

1 reference