(Q35531857)

8 August 2017

title

A novel method for analyzing extremely biased agonism at G protein-coupled receptors (English)

1 reference

G protein-coupled receptor

8 August 2017

main subject

0 references

author name string

Edward L Stahl

1

1 reference

8 August 2017

Lei Zhou

2

1 reference

8 August 2017

Frederick J Ehlert

3

1 reference

8 August 2017

Laura M Bohn

4

1 reference

8 August 2017

publication date

13 February 2015

1 reference

8 August 2017

published in

Molecular Pharmacology

1 reference

8 August 2017

volume

87

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8 August 2017

issue

5

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8 August 2017

page(s)

866-877

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Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist

8 August 2017

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12 July 2018

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12 July 2018

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6'-Guanidinonaltrindole (6'-GNTI) is a G protein-biased κ-opioid receptor agonist that inhibits arrestin recruitment

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes

12 July 2018

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12 July 2018

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12 July 2018

1 reference

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Pharmacological properties of JDTic: a novel kappa-opioid receptor antagonist

12 July 2018

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

12 July 2018

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12 July 2018

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12 July 2018

1 reference

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12 July 2018

1 reference

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Pharmacological relapse prevention in alcohol dependence: from animal models to clinical trials.

12 July 2018

1 reference

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A simple method for estimation of agonist activity at receptor subtypes: comparison of native and cloned M3 muscarinic receptors in guinea pig ileum and transfected cells

12 July 2018

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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus

12 July 2018

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12 July 2018

1 reference

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A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence

12 July 2018

1 reference

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12 July 2018

1 reference

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The two-state model of receptor activation

12 July 2018

1 reference

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Operational models of pharmacological agonism.

12 July 2018

1 reference

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Psychotomimesis mediated by kappa opiate receptors

12 July 2018

1 reference

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First clinical experience with TRV027: pharmacokinetics and pharmacodynamics in healthy volunteers

12 July 2018

1 reference

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Quantifying biased agonism: understanding the links between affinity and efficacy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407734

Measurements of ligand bias and functional affinity.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407734

Functional selectivity and biased receptor signaling.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407734

Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407734

A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407734

Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25680753

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interaction at End-Plate Receptors between Different Choline Derivatives

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25680753

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.114.096503

1 reference

8 August 2017

1 reference

8 August 2017

1 reference