(Q35535617)

8 August 2017

0 references

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (English)

1 reference

8 August 2017

1 reference

7

1 reference

8 August 2017

8

1 reference

8 August 2017

9

1 reference

8 August 2017

22

1 reference

8 August 2017

44

Thomas Quertermous

1 reference

8 August 2017

Ivan Carcamo-Orive

11

0 references

Ville-Petteri Mäkinen

Ville-Petteri Mäkinen

14

0 references

Anubha Mahajan

Anubha Mahajan

16

0 references

Andrea Ganna

Andrea Ganna

15

0 references

Jerome I Rotter

31

Jerome I Rotter

1 reference

8 August 2017

Timothy M Frayling

41

0 references

Michael N Weedon

Michael N Weedon

42

0 references

Markku Laakso

38

Markku Laakso

1 reference

8 August 2017

40

Erik Ingelsson

1 reference

8 August 2017

33

Gerald Reaven

1 reference

8 August 2017

36

Leif Groop

1 reference

8 August 2017

23

Cecilia Lindgren

1 reference

8 August 2017

10

Mark O Goodarzi

1 reference

8 August 2017

30

Eric E Schadt

1 reference

8 August 2017

32

Alan Sinaiko

1 reference

8 August 2017

Heather J Cordell

37

1 reference

ORCID Public Data File 2021

Yen-Chu Chen

13

Yii-Der I Chen

1 reference

8 August 2017

12

Andrew P Morris

1 reference

8 August 2017

Themistocles L Assimes

5

Themistocles L Assimes

1 reference

8 August 2017

Themistocles L Assimes

6

Themistocles L Assimes

1 reference

8 August 2017

Joshua W Knowles

1

1 reference

8 August 2017

Weijia Xie

2

1 reference

8 August 2017

Zhongyang Zhang

3

1 reference

8 August 2017

Indumathi Chennamsetty

4

1 reference

8 August 2017

Xiuqing Guo

17

1 reference

8 August 2017

Fahim Abbasi

18

1 reference

8 August 2017

Danielle M Greenawalt

19

1 reference

8 August 2017

Pek Lum

20

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8 August 2017

Cliona Molony

21

1 reference

8 August 2017

Leslie J Raffel

24

1 reference

8 August 2017

Philip S Tsao

25

1 reference

8 August 2017

RISC (Relationship between Insulin Sensitivity and Cardiovascular Disease) Consortium

26

1 reference

8 August 2017

EUGENE2 (European Network on Functional Genomics of Type 2 Diabetes) Study

27

1 reference

8 August 2017

GUARDIAN (Genetics UndeRlying DIAbetes in HispaNics) Consortium

28

1 reference

8 August 2017

SAPPHIRe (Stanford Asian and Pacific Program for Hypertension and Insulin Resistance) Study

29

1 reference

8 August 2017

Xia Yang

34

1 reference

8 August 2017

Chao A Hsiung

35

1 reference

8 August 2017

Ke Hao

39

1 reference

8 August 2017

Mark Walker

43

1 reference

8 August 2017

language of work or name

English

0 references

publication date

23 March 2015

1 reference

Journal of Clinical Investigation

8 August 2017

published in

1 reference

8 August 2017

volume

125

1 reference

8 August 2017

issue

4

1 reference

8 August 2017

page(s)

1739-1751

1 reference

GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence

8 August 2017

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1 reference

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12 July 2018

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Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans

12 July 2018

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Large-scale association analysis identifies new risk loci for coronary artery disease

12 July 2018

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Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp

12 July 2018

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Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice

12 July 2018

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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

12 July 2018

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

12 July 2018

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

12 July 2018

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

12 July 2018

1 reference

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Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice

12 July 2018

1 reference

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Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes

12 July 2018

1 reference

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Human metabolic individuality in biomedical and pharmaceutical research

12 July 2018

1 reference

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Farnesoid X receptor represses hepatic human APOA gene expression

12 July 2018

1 reference

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A genome-wide association study of metabolic traits in human urine

12 July 2018

1 reference

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A fluorescence method for measurement of glucose transport in kidney cells

12 July 2018

1 reference

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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Hundreds of variants clustered in genomic loci and biological pathways affect human height

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Biological, clinical and population relevance of 95 loci for blood lipids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

METAL: fast and efficient meta-analysis of genomewide association scans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

12 July 2018

1 reference

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

12 July 2018

1 reference

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Apelin is necessary for the maintenance of insulin sensitivity

12 July 2018

1 reference

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A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype

12 July 2018

1 reference

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Multiple advantageous amino acid variants in the NAT2 gene in human populations

12 July 2018

1 reference

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Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2

12 July 2018

1 reference

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Changes in consensus arylamine N-acetyltransferase gene nomenclature

12 July 2018

1 reference

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Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.

12 July 2018

1 reference

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Arylamine N-acetyltransferases.

12 July 2018

1 reference

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Principal components analysis corrects for stratification in genome-wide association studies

12 July 2018

1 reference

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American College of Endocrinology position statement on the insulin resistance syndrome.

12 July 2018

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Generation and analysis of mice with a targeted disruption of the arylamine N-acetyltransferase type 2 gene

12 July 2018

1 reference

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms

12 July 2018

1 reference

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How to measure insulin sensitivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Banting lecture 1988. Role of insulin resistance in human disease

12 July 2018

1 reference

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Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Glucose clamp technique: a method for quantifying insulin secretion and resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Heritability and genetic correlations of insulin sensitivity measured by the euglycaemic clamp.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to type 2 diabetes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Insulin resistance as a predictor of age-related diseases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409020

Assessment of insulin resistance with the insulin suppression test and the euglycemic clamp

26 September 2018

1 reference

12 December 2020

Ethnic differences in drug metabolism

1 reference

12 December 2020

Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes

1 reference

12 December 2020

Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test

1 reference

12 December 2020

Human acetyltransferase polymorphisms

1 reference

12 December 2020

Genetic control of isoniazid metabolism in man

1 reference

12 December 2020

Common familial influences on clustering of metabolic syndrome traits with central obesity and insulin resistance: the Kiel obesity prevention study

1 reference

12 December 2020

Arylamine N-acetyltransferases: from structure to function

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12 December 2020

Identifiers

DOI

10.1172/JCI74692

1 reference

8 August 2017

1 reference

8 August 2017

1 reference