(Q35543229)

English

Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin

scientific article published on 3 August 2011

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin (English)

1 reference

Europe PubMed Central

8 August 2017

0 references

0 references

author name string

Gail A Reif

1

1 reference

Europe PubMed Central

8 August 2017

Tamio Yamaguchi

2

1 reference

Europe PubMed Central

8 August 2017

Emily Nivens

3

1 reference

Europe PubMed Central

8 August 2017

Hiroyuki Fujiki

4

1 reference

Europe PubMed Central

8 August 2017

Cibele S Pinto

5

1 reference

Europe PubMed Central

8 August 2017

Darren P Wallace

6

1 reference

Europe PubMed Central

8 August 2017

publication date

3 August 2011

1 reference

Europe PubMed Central

8 August 2017

American Journal of Physiology - Renal Physiology

1 reference

Europe PubMed Central

8 August 2017

301

1 reference

Europe PubMed Central

8 August 2017

5

1 reference

Europe PubMed Central

8 August 2017

F1005-13

1 reference

Europe PubMed Central

8 August 2017

Receptor protein tyrosine phosphatases are novel components of a polycystin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Cyclic AMP-mediated cyst expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Pharmacology of vasopressin antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Periostin induces proliferation of human autosomal dominant polycystic kidney cells through alphaV-integrin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Non-peptide arginine-vasopressin antagonists: the vaptans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Vasopressin directly regulates cyst growth in polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

PKHD1 gene silencing may cause cell abnormal proliferation through modulation of intracellular calcium in autosomal recessive polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Polycystins: from mechanosensation to gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

A transcriptional network in polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Histopathological analysis of renal cystic epithelia in the Pkd2WS25/- mouse model of ADPKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Developmental expression of urine concentration-associated genes and their altered expression in murine infantile-type polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

OPC-41061, a highly potent human vasopressin V2-receptor antagonist: pharmacological profile and aquaretic effect by single and multiple oral dosing in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Renal accumulation and excretion of cyclic adenosine monophosphate in a murine model of slowly progressive polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Tailoring cAMP-signalling responses through isoform multiplicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Characterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Chloride and fluid secretion by cultured human polycystic kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Anion secretion drives fluid secretion by monolayers of cultured human polycystic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Adult polycystic kidney disease: Studies of the defect in urine concentration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Histogenesis of the renal cysts in adult (autosomal dominant) polycystic kidney disease: a histochemical study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

The clinical utility of renal concentrating capacity in polycystic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

12 July 2018

Practical genetics for autosomal dominant polycystic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Comparison of two doses and dosing regimens of tolvaptan in congestive heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Electrolyte and fluid secretion by cultured human inner medullary collecting duct cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213906

26 September 2018

Bardet–Biedl syndrome highlights the major role of the primary cilium in efficient water reabsorption

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00243.2011

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00243.2011

21 January 2018

Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary Dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00243.2011

21 January 2018

Expansion of extracellular volume in early polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autosomal dominant polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of aquaporins-1 and -2 during nephrogenesis and in autosomal dominant polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The effect of hypervolemia on electrolyte level and and level of volume regulating hormones in patients with autosomal dominant polycystic kidney disease]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloride and fluid secretion in polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased water intake decreases progression of polycystic kidney disease in the PCK rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21816754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPRENAL.00243.2011

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

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