(Q35543612)

8 August 2017

title

Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction (English)

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8 August 2017

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16

Darryl C Zeldin

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8 August 2017

Ryan T Dackor

1

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8 August 2017

Jennifer Cheng

2

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8 August 2017

James W Voltz

3

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8 August 2017

Jeffrey W Card

4

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8 August 2017

Catherine D Ferguson

5

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8 August 2017

Ryan C Garrett

6

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8 August 2017

J Alyce Bradbury

7

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8 August 2017

Laura M DeGraff

8

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8 August 2017

Fred B Lih

9

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8 August 2017

Kenneth B Tomer

10

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8 August 2017

Gordon P Flake

11

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8 August 2017

Gregory S Travlos

12

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8 August 2017

Randle W Ramsey

13

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8 August 2017

Matthew L Edin

14

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8 August 2017

Daniel L Morgan

15

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8 August 2017

publication date

19 August 2011

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American Journal of Physiology - Lung Cellular and Molecular Physiology

8 August 2017

published in

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8 August 2017

volume

301

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8 August 2017

issue

5

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8 August 2017

page(s)

L645-55

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Prostaglandin E2 and the pathogenesis of pulmonary fibrosis.

8 August 2017

cites work

1 reference

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A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice

12 July 2018

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Strategies for treating idiopathic pulmonary fibrosis

12 July 2018

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Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.

12 July 2018

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Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

12 July 2018

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12 July 2018

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Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.

12 July 2018

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Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis

12 July 2018

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Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis

12 July 2018

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Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation

12 July 2018

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12 July 2018

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Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

12 July 2018

1 reference

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The lung as a privileged site for the beneficial actions of PGE2.

12 July 2018

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12 July 2018

IL-13 effector functions

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Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis

12 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

12 July 2018

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12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Molecular monitoring of bleomycin-induced pulmonary fibrosis by cDNA microarray-based gene expression profiling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostaglandin endoperoxide H synthases-1 and -2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogen-stimulated Swiss 3T3 cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production

12 July 2018

1 reference

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Modulation of collagen production by fibroblasts. Effects of chronic exposure to agonists that increase intracellular cyclic AMP

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen

12 July 2018

1 reference

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Simple method of estimating severity of pulmonary fibrosis on a numerical scale

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Tumor necrosis factor interacts with interleukin-1 and interferons to inhibit fibroblast proliferation via fibroblast prostaglandin-dependent and -independent mechanisms.

12 July 2018

1 reference

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In vitro production of B cell growth factor and B cell differentiation factor by peripheral blood mononuclear cells and bronchoalveolar lavage T lymphocytes from patients with idiopathic pulmonary fibrosis

12 July 2018

1 reference

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The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes

12 July 2018

1 reference

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Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Human cyclooxygenase-2 cDNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Inflammatory cell phenotyping of the pulmonary interstitium in idiopathic interstitial pneumonia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Normal human lung fibroblasts differently modulate interleukin-10 and interleukin-12 production by monocytes: implications for an altered immune response in pulmonary chronic inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

Idiopathic Pulmonary Fibrosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213994

American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)

7 December 2018

1 reference

12 December 2020

Nuclear factor-kappaB activation in human monocytes stimulated with lipopolysaccharide is inhibited by fibroblast conditioned medium and exogenous PGE2

1 reference

12 December 2020

Expression of cyclooxygenase-1 and -2 mRNA in rat tissues: tissue-specific difference in the expression of the basal level of mRNA

1 reference

12 December 2020

AN ANALYSIS OF PRESSURE-VOLUME CHARACTERISTICS OF THE LUNGS

1 reference

12 December 2020

The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts

1 reference

12 December 2020

The biochemical and pharmacological manipulation of cellular cyclooxygenase (COX) activity

1 reference

12 December 2020

Interleukin-4 stimulates collagen synthesis by normal and scleroderma fibroblasts in dermal equivalents

1 reference

12 December 2020

Inhibition of the transendothelial migration of human T lymphocytes by prostaglandin E2

1 reference

12 December 2020

Different expression of TNF-alpha receptors and prostaglandin E(2 )Production in normal and fibrotic lung fibroblasts: potential implications for the evolution of the inflammatory process

1 reference

12 December 2020

10.1152/AJPLUNG.00176.2011

Identifiers

DOI

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8 August 2017

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8 August 2017

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