(Q35551003)

8 August 2017

Making yeast tremble: yeast models as tools to study neurodegenerative disorders (English)

1 reference

8 August 2017

Making Yeast Tremble: Yeast Models as Tools to Study Neurodegenerative Disorders (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1385/NMM:4:1-2:133

18 March 2024

1 reference

modelling biological systems

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14528057

18 March 2024

1 reference

https://api.crossref.org/works/10.1385/NMM:4:1-2:133

18 March 2024

1 reference

https://api.crossref.org/works/10.1385/NMM:4:1-2:133

18 March 2024

author name string

Michael Y. Sherman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14528057

18 March 2024

Paul J. Muchowski

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14528057

18 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14528057

18 March 2024

publication date

1 January 2003

1 reference

full work available at URL

8 August 2017

http://www.springerlink.com/index/pdf/10.1385/NMM:4:1-2:133

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1385/NMM:4:1-2:133

18 March 2024

published in

NeuroMolecular Medicine

1 reference

8 August 2017

4

1 reference

8 August 2017

1-2

1 reference

8 August 2017

133-146

1 reference

https://scigraph.springernature.com/pub.10.1385/nmm:4:1-2:133

8 August 2017

0 references

cites work

Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

1 reference

12 December 2020

Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats

1 reference

12 December 2020

The yeast connection to Friedreich ataxia.

1 reference

12 December 2020

Transglutaminase as the agent of neurodegenerative diseases due to polyglutamine expansion.

1 reference

12 December 2020

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

12 December 2020

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

1 reference

12 December 2020

Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment.

1 reference

12 December 2020

Genetic analysis of Batten disease

1 reference

12 December 2020

The ubiquitin-proteasome pathway and pathogenesis of human diseases

1 reference

12 December 2020

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

1 reference

12 December 2020

Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

1 reference

12 December 2020

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

1 reference

12 December 2020

Genetic study of interactions between the cytoskeletal assembly protein sla1 and prion-forming domain of the release factor Sup35 (eRF3) in Saccharomyces cerevisiae

1 reference

12 December 2020

Phenotypic reversal of the btn1 defects in yeast by chloroquine: a yeast model for Batten disease

1 reference

12 December 2020

1 reference

12 December 2020

Folding of newly translated proteins in vivo: the role of molecular chaperones

1 reference

12 December 2020

CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

1 reference

12 December 2020

The unfolded protein response in nutrient sensing and differentiation

1 reference

12 December 2020

Oxygen stress: a regulator of apoptosis in yeast

1 reference

12 December 2020

A yeast mutant showing diagnostic markers of early and late apoptosis

1 reference

12 December 2020

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1 reference

12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

12 December 2020

Transgenic mice in the study of polyglutamine repeat expansion diseases.

1 reference

12 December 2020

Aggresomes: a cellular response to misfolded proteins

1 reference

12 December 2020

Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiae

1 reference

12 December 2020

Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria.

1 reference

12 December 2020

Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

1 reference

12 December 2020

Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors

1 reference

12 December 2020

Rnq1: an epigenetic modifier of protein function in yeast

1 reference

12 December 2020

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

1 reference

12 December 2020

Prions affect the appearance of other prions: the story of [PIN(+)].

1 reference

12 December 2020

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

12 December 2020

Role of mitochondria and C-terminal membrane anchor of Bcl-2 in Bax induced growth arrest and mortality in Saccharomyces cerevisiae

1 reference

12 December 2020

Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones?

1 reference

12 December 2020

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons

1 reference

12 December 2020

Pheromone Induces Programmed Cell Death in S. cerevisiae

1 reference

12 December 2020

A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity

1 reference

12 December 2020

A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion

1 reference

12 December 2020

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

1 reference

12 December 2020

Accumulation of the adenosine triphosphate synthase subunit C in the mnd mutant mouse. A model for neuronal ceroid lipofuscinosis

1 reference

12 December 2020

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

12 December 2020

Intracellular localization of proteasomal degradation of a viral antigen

1 reference

12 December 2020

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

1 reference

12 December 2020

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

1 reference

12 December 2020

Recent Biochemical and Genetic Advances in Our Understanding of Batten's Disease (Ceroid-Lipofuscinosis)

1 reference

12 December 2020

Studies of pH regulation by Btn1p, the yeast homolog of human Cln3p

1 reference

12 December 2020

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

1 reference

12 December 2020

De novo generation of a PrPSc-like conformation in living cells.

1 reference

12 December 2020

The role of Sis1 in the maintenance of the [RNQ+] prion

1 reference

12 December 2020

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

1 reference

12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

12 December 2020

Dynamic association of proteasomal machinery with the centrosome

1 reference

12 December 2020

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

1 reference

12 December 2020

Mammalian Bax triggers apoptotic changes in yeast

1 reference

12 December 2020

Mad cows meet psi-chotic yeast: the expansion of the prion hypothesis

1 reference

12 December 2020

The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast

1 reference

12 December 2020

Investigation of Batten disease with the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.

1 reference

12 December 2020

Protein folding in vivo: the importance of molecular chaperones

1 reference

12 December 2020

Human frataxin maintains mitochondrial iron homeostasis in Saccharomyces cerevisiae.

1 reference

12 December 2020

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

12 December 2020

SIR2 and aging--the exception that proves the rule.

1 reference

12 December 2020

Heat shock causes protein aggregation and reduced protein solubility at the centrosome and other cytoplasmic locations

1 reference

12 December 2020

The unfolding tale of the unfolded protein response

1 reference

12 December 2020

Prionics or the kinetic basis of prion diseases

1 reference

12 December 2020

A yeast model for the study of Batten disease

1 reference

12 December 2020

Apoptosis in yeast: a new model for aging research

1 reference

12 December 2020

The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases

1 reference

12 December 2020

A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions

1 reference

12 December 2020

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

1 reference

12 December 2020

Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?

1 reference

12 December 2020

Systematic screen for human disease genes in yeast

1 reference

12 December 2020

Analysis of the mammalian heat-shock response. Inducible gene expression and heat-shock factor activity

1 reference

12 December 2020

Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

1 reference

12 December 2020

The mammalian endoplasmic reticulum as a sensor for cellular stress

1 reference

12 December 2020

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

1 reference

12 December 2020

Activity and regulation of the centrosome-associated proteasome

1 reference

12 December 2020

Recent advances in the molecular pathogenesis of Friedreich ataxia

1 reference

12 December 2020

Batten disease: evaluation of CLN3 mutations on protein localization and function

1 reference

12 December 2020

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

12 December 2020

Trafficking of the cellular isoform of the prion protein.

1 reference

12 December 2020

Glutathione, oxidative stress and neurodegeneration

1 reference

12 December 2020

Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation

1 reference

12 December 2020

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

12 December 2020

Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.

1 reference

12 December 2020

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

1 reference

12 December 2020

Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue

1 reference

12 December 2020

Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells

1 reference

12 December 2020

Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex

1 reference

12 December 2020

The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination

1 reference

12 December 2020

Genetic pathways that regulate ageing in model organisms

1 reference

12 December 2020

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2

1 reference

12 December 2020

A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

1 reference

12 December 2020

Mutation processes at the protein level: is Lamarck back?

1 reference

12 December 2020

Genetic instabilities of triplet repeat sequences by recombination

1 reference

12 December 2020

Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia

1 reference

12 December 2020

Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae

1 reference

12 December 2020

Apoptosis in yeast: a new model system with applications in cell biology and medicine.

1 reference

12 December 2020

Yeast prions act as genes composed of self-propagating protein amyloids

1 reference

12 December 2020

Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity

1 reference

12 December 2020

Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin

1 reference

12 December 2020

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

1 reference

12 December 2020

Analysis of prion factors in yeast

1 reference

12 December 2020

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

1 reference

12 December 2020

BTN1, a yeast gene corresponding to the human gene responsible for Batten's disease, is not essential for viability, mitochondrial function, or degradation of mitochondrial ATP synthase.

1 reference

12 December 2020

Under respiratory growth conditions, Bcl-x(L) and Bcl-2 are unable to overcome yeast cell death triggered by a mutant Bax protein lacking the membrane anchor

1 reference

12 December 2020

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

12 December 2020

Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

CLN3 protein regulates lysosomal pH and alters intracellular processing of Alzheimer's amyloid-beta protein precursor and cathepsin D in human cells

1 reference

12 December 2020

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 reference

12 December 2020

1 reference

12 December 2020

Ubiquitin-mediated proteolysis centers in HeLa cells: indication from studies of an inhibitor of the chymotrypsin-like activity of the proteasome

1 reference

12 December 2020

Identifiers

DOI

1 reference

Dimensions Publication ID

8 August 2017

1003073808

0 references

Fatcat ID

release_tfjk66tkzbfevnimotl2yb5jrm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tfjk66tkzbfevnimotl2yb5jrm

24 November 2022

mapped directly with Wikidata item

1 reference