(Q35551725)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Nikolas Balanis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Masaaki Yoshigi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

William P Schiemann

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Cathleen R Carlin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

publication date

21 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

4288-4301

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3216655/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3216655/fullTextXML

inferred from PubMed Central ID database lookup

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12 July 2018

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12 July 2018

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12 July 2018

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The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

12 July 2018

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12 July 2018

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Adhesion signaling - crosstalk between integrins, Src and Rho.

12 July 2018

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Fascin regulates prostate cancer cell invasion and is associated with metastasis and biochemical failure in prostate cancer

12 July 2018

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Growth factors and cytokines in wound healing

12 July 2018

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12 July 2018

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12 July 2018

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Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation

12 July 2018

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Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis

12 July 2018

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12 July 2018

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Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

12 July 2018

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12 July 2018

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Filopodia: the fingers that do the walking

12 July 2018

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Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer

12 July 2018

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Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src

12 July 2018

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Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane

12 July 2018

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Role of fascin in filopodial protrusion

12 July 2018

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Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

12 July 2018

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Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells

12 July 2018

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STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines

12 July 2018

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An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

12 July 2018

1 reference

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Gab1 signaling is regulated by EGF receptor sorting in early endosomes

12 July 2018

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p130Cas: a versatile scaffold in signaling networks

12 July 2018

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Spatiotemporal dynamics of RhoA activity in migrating cells

12 July 2018

1 reference

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Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

12 July 2018

1 reference

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Cell migration during gastrulation

12 July 2018

1 reference

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Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

12 July 2018

1 reference

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The role of protein-tyrosine phosphatase 1B in integrin signaling

12 July 2018

1 reference

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The interplay between Src and integrins in normal and tumor biology

12 July 2018

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Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Extracellular matrix signaling through growth factor receptors during wound healing

12 July 2018

1 reference

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Epithelial-mesenchymal transitions in development and pathologies

12 July 2018

1 reference

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Host microenvironment in breast cancer development: epithelial-cell-stromal-cell interactions and steroid hormone action in normal and cancerous mammary gland

12 July 2018

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Directional motility induced by epidermal growth factor requires Cdc42.

12 July 2018

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Trafficking of the ErbB receptors and its influence on signaling

12 July 2018

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12 July 2018

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Cellular motility driven by assembly and disassembly of actin filaments

12 July 2018

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Mechanism of filopodia initiation by reorganization of a dendritic network

12 July 2018

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Integrins: bidirectional, allosteric signaling machines

12 July 2018

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The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core

12 July 2018

1 reference

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Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

12 July 2018

1 reference

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c-Src tyrosine phosphorylation of epidermal growth factor receptor, P190 RhoGAP, and focal adhesion kinase regulates diverse cellular processes

12 July 2018

1 reference

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N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

12 July 2018

1 reference

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RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Phosphorylation of p190 on Tyr1105 by c-Src is necessary but not sufficient for EGF-induced actin disassembly in C3H10T1/2 fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Untangling the ErbB signalling network

12 July 2018

1 reference

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Increased expression of fascin, motility associated protein, in cell cultures derived from ovarian cancer and in borderline and carcinomatous ovarian tumors

12 July 2018

1 reference

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E3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes

12 July 2018

1 reference

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The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain

12 July 2018

1 reference

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Rho GTPases. Integrating integrin signaling

12 July 2018

1 reference

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EGF receptor residues leu(679), leu(680) mediate selective sorting of ligand-receptor complexes in early endosomal compartments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Phosphorylation of the p190 RhoGAP N-terminal domain by c-Src results in a loss of GTP binding activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Cell adhesion and motility depend on nanoscale RGD clustering.

12 July 2018

1 reference

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Actin machinery: pushing the envelope.

12 July 2018

1 reference

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Biophysical integration of effects of epidermal growth factor and fibronectin on fibroblast migration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Bone sialoprotein supports breast cancer cell adhesion proliferation and migration through differential usage of the alpha(v)beta3 and alpha(v)beta5 integrins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

The cytoplasmic juxtamembrane domain of the epidermal growth factor receptor contains a novel autonomous basolateral sorting determinant

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Integrin-mediated cell adhesion: the extracellular face

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Mutation-deletion analysis of a Ca(2+)-dependent phospholipid binding (CaLB) domain within p120 GAP, a GTPase-activating protein for p21 ras.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

c-Src phosphorylates epidermal growth factor receptor on tyrosine 845.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Basal lamina formation by normal and transformed mouse mammary epithelial cells duplicated in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

12 July 2018

Protein-tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Mechanism of phosphorylation of the epidermal growth factor receptor at threonine 669.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

A negative feedback loop attenuates EGF-induced morphological changes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Interaction between the epidermal growth factor receptor and phosphoinositide kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Variants of 3T3 cells lacking mitogenic response to epidermal growth factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

The juxtamembrane region of EGFR takes center stage.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

Quantification of stretch‐induced cytoskeletal remodeling in vascular endothelial cells by image processing

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216655

[Tumours and inflammatory liver diseases]

26 September 2018

1 reference

12 December 2020

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

12 December 2020

Epidermal growth factor induces acute matrix contraction and subsequent calpain-modulated relaxation

1 reference

12 December 2020

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

12 December 2020

Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia

1 reference

12 December 2020

Src autoinhibition: let us count the ways

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E10-08-0700

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21937717%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

21937717

1 reference