(Q35553592)

English

The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia

scientific article published on 8 September 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

chronic myeloid leukemia

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Richard D Press

object named as

Richard D Press

9

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object named as

Brian J Druker

14

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author name string

Thomas O'Hare

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Matthew S Zabriskie

2

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Europe PubMed Central

PubMed publication ID

8 August 2017

Christopher A Eide

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Anupriya Agarwal

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Lauren T Adrian

5

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Huihong You

6

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Amie S Corbin

7

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Fei Yang

8

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Victor M Rivera

10

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Julie Toplin

11

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Europe PubMed Central

PubMed publication ID

8 August 2017

Stephane Wong

12

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Europe PubMed Central

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8 August 2017

Michael W Deininger

13

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Europe PubMed Central

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8 August 2017

language of work or name

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publication date

8 September 2011

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Europe PubMed Central

PubMed publication ID

8 August 2017

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Europe PubMed Central

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8 August 2017

118

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Europe PubMed Central

PubMed publication ID

8 August 2017

19

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8 August 2017

5250-5254

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

The ABL switch control inhibitor DCC-2036 is active against the chronic myeloid leukemia mutant BCR-ABLT315I and exhibits a narrow resistance profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Exon 7 deletion in the bcr-abl gene is frequent in chronic myeloid leukemia patients and is not correlated with resistance against imatinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

BCR-ABL truncation due to premature translation termination as a mechanism of resistance to kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

An intron-derived insertion/truncation mutation in the BCR-ABL kinase domain in chronic myeloid leukemia patients undergoing kinase inhibitor therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Overriding imatinib resistance with a novel ABL kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Autoinhibition of Bcr-Abl through its SH3 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Structural basis for the autoinhibition of c-Abl tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

A myristoyl/phosphotyrosine switch regulates c-Abl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Analysis of the structural basis of specificity of inhibition of the Abl kinase by STI571.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

12 July 2018

Successful treatment using omacetaxine for a patient with CML and BCR-ABL1 [corrected] 35INS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

26 September 2018

ABL alternative splicing is quite frequent in normal population - letter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

26 September 2018

Functional characterization of an activating TEK mutation in acute myeloid leukemia: a cellular context-dependent activating mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

26 September 2018

BCR-ABL alternative splicing as a common mechanism for imatinib resistance: evidence from molecular dynamics simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

26 September 2018

Characterization of BCR-ABL deletion mutants from patients with chronic myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217407

26 September 2018

Variant isoforms of BCR-ABL1 in chronic myelogenous leukemia reflect alternative splicing of ABL1 in normal tissue - letter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21908430

12 December 2020

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Identifiers

10.1182/BLOOD-2011-05-349191

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

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