(Q35556455)

8 August 2017

title

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer (English)

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8 August 2017

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Mark Kester

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Kevin F Staveley-O'Carroll

8 August 2017

10

object named as

Kevin F Staveley-O'Carroll

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8 August 2017

12

Todd E Fox

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8 August 2017

Yixing Jiang

1

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8 August 2017

Nicole A DiVittore

2

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8 August 2017

James M Kaiser

3

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8 August 2017

Sriram S Shanmugavelandy

4

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8 August 2017

Jennifer L Fritz

5

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8 August 2017

Yasser Heakal

6

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8 August 2017

Hephzibah Rani S Tagaram

7

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8 August 2017

Hua Cheng

8

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8 August 2017

Myles C Cabot

9

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8 August 2017

Melissa A Tran

11

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8 August 2017

Brian M Barth

13

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8 August 2017

publication date

1 October 2011

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Cancer Biology and Therapy

8 August 2017

published in

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8 August 2017

volume

12

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8 August 2017

issue

7

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8 August 2017

page(s)

574-585

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Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance

8 August 2017

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27 July 2018

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27 July 2018

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Ceramide regulates gemcitabine-induced senescence and apoptosis in human pancreatic cancer cell lines

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development

27 July 2018

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27 July 2018

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27 July 2018

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BCL-2 functions as an activator of the AKT signaling pathway in pancreatic cancer

27 July 2018

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Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells

27 July 2018

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27 July 2018

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Paclitaxel and ceramide co-administration in biodegradable polymeric nanoparticulate delivery system to overcome drug resistance in ovarian cancer

27 July 2018

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K-ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment

27 July 2018

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27 July 2018

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Sphingolipids as modulators of cancer cell death: potential therapeutic targets

27 July 2018

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27 July 2018

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27 July 2018

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Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

27 July 2018

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Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides.

27 July 2018

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Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines

27 July 2018

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Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels

27 July 2018

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Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells

27 July 2018

1 reference

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Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

27 July 2018

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Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions

27 July 2018

1 reference

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Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer

27 July 2018

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27 July 2018

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Protein kinase C: a target for therapy in pancreatic cancer

27 July 2018

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Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy

21 January 2018

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https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate.

21 January 2018

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https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Metabolism of short-chain ceramide by human cancer cells--implications for therapeutic approaches.

21 January 2018

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Gemcitabine-mediated apoptosis is associated with increased CD95 surface expression but is not inhibited by DN-FADD in Colo357 pancreatic cancer cells

21 January 2018

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https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.12.7.15971

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218384

Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218384

Change in pharmacokinetic and pharmacodynamic behavior of gemcitabine in human tumor xenografts upon entrapment in vesicular phospholipid gels

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218384

P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218384

Decreasing the apoptotic threshold of tumor cells through protein kinase C inhibition and sphingomyelinase activation increases tumor killing by ionizing radiation

15 November 2018

1 reference

12 December 2020

Loss of ceramide production confers resistance to radiation-induced apoptosis

1 reference

12 December 2020

Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma

1 reference

12 December 2020

Radiation-induced apoptosis--the ceramide-SAPK signaling pathway and clinical aspects

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.12.7.15971

1 reference

8 August 2017

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8 August 2017

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