(Q35557848)

English

Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells.

scientific article published on 31 May 2011

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scholarly article

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Europe PubMed Central

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2 February 2020

Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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inferred from title

Rosalyn D Abbott

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

James C. Iatridis

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Devina Purmessur

1

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Europe PubMed Central

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2 February 2020

Rachel M Schek

2

1 reference

Europe PubMed Central

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2 February 2020

Bryan A Ballif

4

1 reference

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2 February 2020

Karolyn E Godburn

5

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2 February 2020

publication date

31 May 2011

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Europe PubMed Central

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2 February 2020

Arthritis Research and Therapy

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

13

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2 February 2020

3

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2 February 2020

R81

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

https://scigraph.springernature.com/pub.10.1186/ar3344

0 references

Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

1 reference

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12 July 2018

Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Notochordal intervertebral disc cells: sensitivity to nutrient deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Matrix metalloprotease inhibitors suppress initiation and progression of chondrogenic differentiation of mesenchymal stromal cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

MSC response to pH levels found in degenerating intervertebral discs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Future perspectives of cell-based therapy for intervertebral disc disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Matrix synthesis and degradation in human intervertebral disc degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Molecular phenotypes of notochordal cells purified from immature nucleus pulposus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Tumor necrosis factor-alpha modulates matrix production and catabolism in nucleus pulposus tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Clusterin expression in adult human normal and osteoarthritic articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Expression of clusterin in the superficial zone of bovine articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

12 July 2018

Induction of intervertebral disc-like cells from adult mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Feasibility of a stem cell therapy for intervertebral disc degeneration

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Intervertebral disc cell-mediated mesenchymal stem cell differentiation.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Toward an optimum system for intervertebral disc organ culture: TGF-beta 3 enhances nucleus pulposus and anulus fibrosus survival and function through modulation of TGF-beta-R expression and ERK signaling.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Suppression of genes related to hypertrophy and osteogenesis in committed human mesenchymal stem cells cultured on novel nitrogen-rich plasma polymer coatings.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

A comparative proteomic analysis of human and rat embryonic cerebrospinal fluid.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Hypertrophic differentiation and calcification during intervertebral disc degeneration.

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage

1 reference

https://api.crossref.org/works/10.1186%2FAR3344

21 January 2018

Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

26 September 2018

In vitro study on interaction between human nucleus pulposus cells and mesenchymal stem cells through paracrine stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

26 September 2018

Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

26 September 2018

Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

26 September 2018

The development and growth of the intervertebral disc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218891

26 September 2018

Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21627827

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inferred from PubMed ID database lookup

Disc regeneration therapy using marrow mesenchymal cell transplantation: a report of two case studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21627827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tenascin in the human intervertebral disc: alterations with aging and disc degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21627827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21627827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21627827%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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