(Q35558050)

8 August 2017

title

Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes (English)

1 reference

8 August 2017

7

Bob van de Water

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author name string

Yinghui Zhang

1

1 reference

8 August 2017

Marja Moerkens

2

1 reference

8 August 2017

Sreenivasa Ramaiahgari

3

1 reference

8 August 2017

Hans de Bont

4

1 reference

8 August 2017

Leo Price

5

1 reference

8 August 2017

John Meerman

6

1 reference

8 August 2017

Bob van de Water

7

1 reference

8 August 2017

language of work or name

1 reference

19 May 2011

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8 August 2017

published in

Breast Cancer Research

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8 August 2017

volume

13

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8 August 2017

issue

3

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8 August 2017

page(s)

R52

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Creative Commons Attribution 2.0 Generic

8 August 2017

copyright license

start time

19 May 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/bcr2883

0 references

cites work

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Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells

12 July 2018

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12 July 2018

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Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells

12 July 2018

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12 July 2018

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Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways.

12 July 2018

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Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells

12 July 2018

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BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells

12 July 2018

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Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Molecular mechanisms of endocrine resistance and their implication in the therapy of breast cancer

12 July 2018

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Her2 cross talk and therapeutic resistance in breast cancer

12 July 2018

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12 July 2018

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Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant

12 July 2018

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Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function

12 July 2018

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Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance

12 July 2018

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Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells

12 July 2018

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Pathways to tamoxifen resistance

12 July 2018

1 reference

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Crosstalk between IGF signaling and steroid hormone receptors in breast cancer

12 July 2018

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Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant

12 July 2018

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Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor.

12 July 2018

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Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

12 July 2018

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Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer

12 July 2018

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Synergy between PI3K/Akt and Raf/MEK/ERK pathways in IGF-1R mediated cell cycle progression and prevention of apoptosis in hematopoietic cells

12 July 2018

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A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

12 July 2018

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12 July 2018

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Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells

12 July 2018

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Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells

12 July 2018

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Control of cell survival by IGF signaling pathways.

12 July 2018

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Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Function of the IGF-I receptor in breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

New colorimetric cytotoxicity assay for anticancer-drug screening

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Prognostic significance of IGF-1R expression in patients treated with breast-conserving surgery and radiation therapy

12 July 2018

1 reference

Sulforhodamine B colorimetric assay for cytotoxicity screening.

21 January 2018

1 reference

Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state.

21 January 2018

1 reference

A random variance model for detection of differential gene expression in small microarray experiments

21 January 2018

1 reference

Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218939

Molecular mechanisms of mutual effects of the pathological processes during combination of diabetes mellitus and cancer

26 September 2018

1 reference

12 December 2020

Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas

1 reference

12 December 2020

Tamoxifen induces accumulation of MCF 7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle

1 reference

12 December 2020

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

1 reference

12 December 2020

Tamoxifen in the treatment of breast cancer

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12 December 2020

Endocrine resistance in breast cancer: what really matters?

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12 December 2020

Hormono-biological therapy in metastatic breast cancer: preclinical evidence, clinical studies and future directions

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12 December 2020

Identifiers

DOI

10.1186/BCR2883

1 reference

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference