(Q35558312)

8 August 2017

1 reference

title

Role of AML1/Runx1 in the pathogenesis of hematological malignancies (English)

1 reference

8 August 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

20 March 2024

author name string

Mineo Kurokawa

1

1 reference

8 August 2017

Hisamaru Hirai

2

1 reference

8 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14556655

20 March 2024

publication date

1 October 2003

1 reference

full work available at URL

8 August 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.2003.tb01364.x

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14556655

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1349-7006.2003.tb01364.x

20 March 2024

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1349-7006.2003.tb01364.x

20 March 2024

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

20 March 2024

1 reference

8 August 2017

volume

94

1 reference

8 August 2017

issue

10

1 reference

8 August 2017

page(s)

841-846

1 reference

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

8 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Runx1/AML1 in leukemia: disrupted association with diverse protein partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

A role for hematopoietic stem cells in promoting angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

AML1 interconnected pathways of leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Molecular tracking of leukemogenesis in a triplet pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

New mechanisms of AML1 gene alteration in hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

The Runx genes as dominant oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01364.X

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

1

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

20 March 2024

3

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo

20 March 2024

10

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Diminution of the AML1 transcription factor function causes differential effects on the fates of CD4 and CD8 single-positive T cells

20 March 2024

14

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Overexpression of AML1 transcription factor drives thymocytes into the CD8 single-positive lineage

20 March 2024

15

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

20 March 2024

17

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

20 March 2024

18

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

20 March 2024

19

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

20 March 2024

36

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia

20 March 2024

43

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01364.X

20 March 2024

Identifiers

1 reference

8 August 2017

1 reference