(Q35559481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

Luis Augusto Aguirre Pérez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

José Luis Gómez-Skarmeta

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Diego Franco

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Miguel Manzanares

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

M Eva Alonso

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Claudio Badía-Careaga

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Isabel Rollán

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Cristina Arias

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ana Fernández-Miñán

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Elena López-Jiménez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Amelia Aránega

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

publication date

17 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

5 March 2020

copyright license

start time

17 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4416339/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Obesity-associated variants within FTO form long-range functional connections with IRX3

27 July 2018

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Atrial Fibrillation associated chromosome 4q25 variants are not associated with PITX2c expression in human adult left atrial appendages

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes

27 July 2018

1 reference

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A high-resolution map of the three-dimensional chromatin interactome in human cells

27 July 2018

1 reference

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27 July 2018

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Exaptation of transposable elements into novel cis-regulatory elements: is the evidence always strong?

27 July 2018

1 reference

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An integrated encyclopedia of DNA elements in the human genome

27 July 2018

1 reference

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Transposable elements: an abundant and natural source of regulatory sequences for host genes.

27 July 2018

1 reference

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TBX5 drives Scn5a expression to regulate cardiac conduction system function

27 July 2018

1 reference

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Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

27 July 2018

1 reference

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Meta-analysis identifies six new susceptibility loci for atrial fibrillation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Topological domains in mammalian genomes identified by analysis of chromatin interactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Transcriptional enhancers in development and disease

27 July 2018

1 reference

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A decade of 3C technologies: insights into nuclear organization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Potential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Genomewide association studies and assessment of the risk of disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Development of the pacemaker tissues of the heart.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Genomic views of distant-acting enhancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Natural antisense transcript of natriuretic peptide precursor A (NPPA): structural organization and modulation of NPPA expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Histone modifications at human enhancers reflect global cell-type-specific gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Functional autonomy of distant-acting human enhancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

In situ hybridization analysis of chick embryos in whole-mount and tissue sections.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Atrial fibrillation: evidence for genetically determined disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

New insights into the importance of aminopeptidase A in hypertension

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

An evaluation of 3C-based methods to capture DNA interactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Quantitative analysis of chromosome conformation capture assays (3C-qPCR).

27 July 2018

1 reference

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Molecular pathway for the localized formation of the sinoatrial node

27 July 2018

1 reference

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VISTA Enhancer Browser--a database of tissue-specific human enhancers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Applied bioinformatics for the identification of regulatory elements

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Atrial fibrillation: hypertension as a causative agent, risk factor for complications, and potential therapeutic target

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

A monomeric red fluorescent protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pathophysiology and prevention of atrial fibrillation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Functional interpretation of non-coding sequence variation: concepts and challenges

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Homeobox transcription factor Pitx2: The rise of an asymmetry gene in cardiogenesis and arrhythmogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Characterization of Pitx2c expression in the mouse heart using a reporter transgene.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Common variants in KCNN3 are associated with lone atrial fibrillation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Variants conferring risk of atrial fibrillation on chromosome 4q25.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

The beta-globin nuclear compartment in development and erythroid differentiation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Hypertension and angiotensin II hypersensitivity in aminopeptidase A-deficient mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Pitx2 participates in the late phase of the pathway controlling left-right asymmetry

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

The regulation of myogenin gene expression during the embryonic development of the mouse

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416339

Atrial fibrillation guidelines across the Atlantic: a comparison of the current recommendations of the European Society of Cardiology/European Heart Rhythm Association/European Association of Cardiothoracic Surgeons, the American College of Cardiolog

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12915-015-0138-0

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12915-015-0138-0

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25888893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25888893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12915-015-0138-0

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

25888893

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25888893%20AND%20SRC:MED&resulttype=core&format=json