(Q35559497)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

0 references

1 reference

hospital-acquired infection

1 reference

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Fabienne Venet

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

9

Bernard Allaouchiche

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Caroline Guignant

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Alain Lepape

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Xin Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Hakim Kherouf

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Laure Denis

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Françoise Poitevin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Christophe Malcus

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Aurélie Chéron

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

François Gueyffier

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Guillaume Monneret

12

1 reference

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25 January 2020

publication date

21 March 2011

1 reference

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25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

15

1 reference

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25 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

R99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Upregulation of the pro-apoptotic genes BID and FAS in septic shock patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Immunotherapy for sepsis--a new approach against an ancient foe.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

B and T lymphocyte attenuator tempers early infection immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 and its ligands in tolerance and immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

The pathophysiology and treatment of sepsis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Normal responses to injury prevent systemic inflammation and can be immunosuppressive

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Perioperative gene expression analysis for prediction of postoperative sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Sepsis in European intensive care units: results of the SOAP study.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

Negative signaling contributes to T-cell anergy in trauma patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219369

The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration

24 October 2018

1 reference

12 December 2020

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

1 reference

12 December 2020

Editorial: PD-1, a new target for sepsis treatment: better late than never

1 reference

12 December 2020

Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock

1 reference

12 December 2020

Nosocomial infection after septic shock among intensive care unit patients

1 reference

12 December 2020

Induction of global anergy rather than inhibitory Th2 lymphokines mediates posttrauma T cell immunodepression

1 reference

12 December 2020

Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans

1 reference

12 December 2020

Analytical requirements for measuring monocytic human lymphocyte antigen DR by flow cytometry: application to the monitoring of patients with septic shock

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC10112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418617%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21418617

1 reference