(Q35559953)

8 August 2017

title

Regulation of IFN-gamma signaling is essential for the cytotoxic activity of CD8(+) T cells (English)

1 reference

8 August 2017

G Z Tau

1

1 reference

8 August 2017

S N Cowan

2

1 reference

8 August 2017

J Weisburg

3

1 reference

8 August 2017

N S Braunstein

4

1 reference

8 August 2017

P B Rothman

5

1 reference

8 August 2017

language of work or name

English

0 references

publication date

1 November 2001

1 reference

8 August 2017

published in

Journal of Immunology

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8 August 2017

volume

167

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8 August 2017

issue

10

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8 August 2017

page(s)

5574-5582

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Negative cross-talk between interleukin-3 and interleukin-11 is mediated by suppressor of cytokine signalling-3 (SOCS-3)

8 August 2017

cites work

1 reference

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IL-10 attenuates IFN-alpha-activated STAT1 in the liver: involvement of SOCS2 and SOCS3

12 July 2018

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Interferon gamma signaling alters the function of T helper type 1 cells.

12 July 2018

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

12 July 2018

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CD8+ T Cell Effector Mechanisms in Resistance to Infection

12 July 2018

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Incomplete CD8(+) T lymphocyte differentiation as a mechanism for subdominant cytotoxic T lymphocyte responses to a viral antigen

12 July 2018

1 reference

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SOCS-1 can suppress CD3zeta- and Syk-mediated NF-AT activation in a non-lymphoid cell line

12 July 2018

1 reference

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Proapoptotic functions of cytotoxic lymphocyte granule constituents in vitro and in vivo.

12 July 2018

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Biologic functions of the IFN-gamma receptors

12 July 2018

1 reference

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Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma.

12 July 2018

1 reference

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SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation

12 July 2018

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Tumor necrosis factor receptor and Fas signaling mechanisms.

12 July 2018

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Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

12 July 2018

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Phosphatidylinositol 3-kinase-dependent and -independent cytolytic effector functions

12 July 2018

1 reference

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Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells

12 July 2018

1 reference

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Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

12 July 2018

1 reference

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Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction

12 July 2018

1 reference

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Sensitivity of S49.1 cells to anti-CD95 (Fas/Apo-1)-induced apoptosis: effects of CD95, Bcl-2 or Bcl-x transduction

12 July 2018

1 reference

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IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Selective induction of CD8+ cytotoxic T lymphocyte effector function by staphylococcus enterotoxin B.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

How cells respond to interferons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Ca2+ signaling modulates cytolytic T lymphocyte effector functions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Cytokines induce the development of functionally heterogeneous T helper cell subsets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

T cell functions in granulocyte/macrophage colony-stimulating factor deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

A family of cytokine-inducible inhibitors of signalling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

IL-2 induces Fas ligand/Fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Cellular responses to interferon-gamma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

The IFN gamma receptor: a paradigm for cytokine receptor signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Interferon-gamma: biology and role in pathogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Distinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human mo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Determination of lymphocyte division by flow cytometry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Lymphocyte responses and cytokines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Cytokines and growth factors signal through tyrosine phosphorylation of a family of related transcription factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Gamma chain-associated cytokine receptors signal through distinct transducing factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Dominance and crypticity of T cell antigenic determinants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Induction of apoptosis in mature T cells by tumour necrosis factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Partial activation of CD8+ T cells by a self-derived peptide

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Human lymphocyte response to phytomitogens in vitro: normal, agammaglobulinemic and paraproteinemic individuals

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Role of a pertussis toxin substrate in the control of lectin-induced cap formation in human neutrophils

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Tyrosine phosphorylation is an obligatory event in IL-2 secretion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Roles of alpha beta and gamma delta T cell subsets in viral immunity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Characterization and use of monoclonal and polyclonal antibodies against the mouse interferon-gamma receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4416493

The lectin concanavalin A stimulates a protein-tyrosine kinase p72syk in peripheral blood lymphocytes

24 October 2018

1 reference

12 December 2020

CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells

1 reference

12 December 2020

A simple method for evaluating the rejection of grafted spleen cells by flow cytometry and tracing adoptively transferred cells by light microscopy

1 reference

12 December 2020

Early calcium signaling and calcium requirements for the IL-2 receptor expression and IL-2 production in stimulated lymphocytes

1 reference

12 December 2020

Cytotoxic lymphocytes. Two ways to kill target cells

1 reference

12 December 2020

IL-4 diminishes perforin-mediated and increases Fas ligand-mediated cytotoxicity In vivo

1 reference

12 December 2020

A role for IL-5 in the induction of cytotoxic T lymphocytes in vivo

1 reference

12 December 2020

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes

1 reference

12 December 2020

Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells

1 reference

12 December 2020

Immune response in mice that lack the interferon-gamma receptor

1 reference

12 December 2020

Quantitative assay for lectin-induced cytoagglutination by means of an electronic particle-counting technique

1 reference

12 December 2020

10.4049/JIMMUNOL.167.10.5574

Identifiers

DOI

1 reference

8 August 2017

1 reference

8 August 2017

1 reference