(Q35560378)

8 August 2017

1 reference

title

mTOR signaling to translation (English)

1 reference

8 August 2017

mTOR Signaling to Translation (English)

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

21 March 2024

author name string

A. C. Gingras

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560958

21 March 2024

B. Raught

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560958

21 March 2024

N. Sonenberg

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14560958

21 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14560958

21 March 2024

publication date

1 January 2004

1 reference

full work available at URL

8 August 2017

http://link.springer.com/content/pdf/10.1007/978-3-642-18930-2_11.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Current Topics in Microbiology and Immunology

21 March 2024

published in

1 reference

8 August 2017

279

1 reference

8 August 2017

169-197

1 reference

Immunopharmacology of rapamycin

8 August 2017

1

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

HEAT repeats in the Huntington's disease protein

21 March 2024

3

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

TOR controls translation initiation and early G1 progression in yeast

21 March 2024

4

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors

21 March 2024

5

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

21 March 2024

6

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

21 March 2024

7

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The TOR (target of rapamycin) signal transduction pathway regulates the stability of translation initiation factor eIF4G in the yeast Saccharomyces cerevisiae

21 March 2024

8

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

FAT: a novel domain in PIK-related kinases

21 March 2024

10

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Continuous protein synthesis is required to maintain the probability of entry into S phase

21 March 2024

11

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A signaling pathway to translational control

21 March 2024

12

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

21 March 2024

13

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The mammalian target of rapamycin phosphorylates sites having a (Ser/Thr)-Pro motif and is activated by antibodies to a region near its COOH terminus

21 March 2024

14

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 March 2024

15

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 March 2024

16

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 March 2024

17

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The TOR signaling cascade regulates gene expression in response to nutrients

21 March 2024

18

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 March 2024

20

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 March 2024

21

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.

21 March 2024

22

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E.

21 March 2024

23

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Gene-specific regulation by general translation factors

21 March 2024

24

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases

21 March 2024

25

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes

21 March 2024

26

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The Cln3 cyclin is down-regulated by translational repression and degradation during the G1 arrest caused by nitrogen deprivation in budding yeast

21 March 2024

28

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 March 2024

29

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 March 2024

30

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Regulation of translation initiation by FRAP/mTOR

21 March 2024

31

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

21 March 2024

32

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Regulation of translation initiation by FRAP/mTOR

21 March 2024

34

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

21 March 2024

35

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics

21 March 2024

36

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Topological characteristics of helical repeat proteins

21 March 2024

37

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

21 March 2024

38

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

21 March 2024

39

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111)

21 March 2024

40

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Internal ribosome entry sites in eukaryotic mRNA molecules

21 March 2024

41

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Internal ribosome initiation of translation and the control of cell death.

21 March 2024

44

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs

21 March 2024

45

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 March 2024

47

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway

21 March 2024

48

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

21 March 2024

50

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast

21 March 2024

51

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study

21 March 2024

52

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Sirolimus: a comprehensive review

21 March 2024

53

2

1903

B.D. Kahan

2001

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A quantitative molecular model for modulation of mammalian translation by the eIF4E-binding protein 1.

21 March 2024

54

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

21 March 2024

55

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

21 March 2024

56

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

21 March 2024

58

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E

21 March 2024

59

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

An analysis of vertebrate mRNA sequences: intimations of translational control

21 March 2024

60

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Carbon- and nitrogen-quality signaling to translation are mediated by distinct GATA-type transcription factors

21 March 2024

61

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

21 March 2024

62

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

21 March 2024

64

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Model for the regulation of mRNA translation applied to haemoglobin synthesis

21 March 2024

65

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Translational control of protein synthesis

21 March 2024

66

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts

21 March 2024

67

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Modulation of transcription of rRNA genes by rapamycin

21 March 2024

68

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Isolation of translationally controlled mRNAs by differential screening.

21 March 2024

73

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo

21 March 2024

74

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies

21 March 2024

75

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 March 2024

76

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

21 March 2024

77

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

21 March 2024

78

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

21 March 2024

79

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

21 March 2024

80

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

21 March 2024

82

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

21 March 2024

83

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

21 March 2024

84

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 March 2024

85

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Translational control of the antiapoptotic function of Ras.

21 March 2024

86

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

21 March 2024

87

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae

21 March 2024

88

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA.

21 March 2024

90

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

A cell cycle-dependent internal ribosome entry site

21 March 2024

91

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.

21 March 2024

92

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F

21 March 2024

98

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling

21 March 2024

99

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

TOR, a central controller of cell growth

21 March 2024

100

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

PIK3CA is implicated as an oncogene in ovarian cancer.

21 March 2024

101

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

21 March 2024

103

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation

21 March 2024

104

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

TOR signalling and control of cell growth

21 March 2024

105

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

21 March 2024

106

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

21 March 2024

108

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway

21 March 2024

110

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 March 2024

111

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway

21 March 2024

112

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

Messenger RNA translation state: the second dimension of high-throughput expression screening

21 March 2024

113

1 reference

https://api.crossref.org/works/10.1007/978-3-642-18930-2_11

21 March 2024

Identifiers

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14560958

21 March 2024

1 reference