(Q35561779)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

review article

1 reference

title

The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

John E Donelson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Mary E Wilson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Biochemical Parasitology

20 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

132

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

1-16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

Leishmaniasis. Public health aspects and control

20 December 2019

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7 January 2021

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7 January 2021

The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63)

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7 January 2021

Activation mechanism of pro-astacin: role of the pro-peptide, tryptic and autoproteolytic cleavage and importance of precise amino-terminal processing.

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7 January 2021

Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus

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7 January 2021

The promastigote surface protease of Leishmania

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7 January 2021

Mutational and functional analysis of the Leishmania surface metalloproteinase GP63: similarities to matrix metalloproteinases

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7 January 2021

Expression of lipophosphoglycan, high-molecular weight phosphoglycan and glycoprotein 63 in promastigotes and amastigotes of Leishmania mexicana

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7 January 2021

Leishmania gp63 molecule implicated in cellular adhesion lacks an Arg-Gly-Asp sequence.

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7 January 2021

Characterization of the promastigote surface protease of Leishmania as a membrane-bound zinc endopeptidase

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7 January 2021

Differentially expressed Leishmania major gp63 genes encode cell surface leishmanolysin with distinct signals for glycosylphosphatidylinositol attachment.

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7 January 2021

Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated.

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7 January 2021

Molecular cloning of the major surface antigen of leishmania

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7 January 2021

Analysis of the active site and activation mechanism of the Leishmania surface metalloproteinase GP63.

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7 January 2021

Sequence heterogeneity and polymorphic gene arrangements of the Leishmania guyanensis gp63 genes

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7 January 2021

Posttranslational regulation of a Leishmania HEXXH metalloprotease (gp63). The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidylinositol addition sites on N-terminal end cleavage, intracellul

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7 January 2021

The protein sequence predicted from a Leishmania guyanensis gp63 major surface glycoprotein gene is divergent as compared with other Leishmania species

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7 January 2021

The Leishmania genome project: new insights into gene organization and function

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7 January 2021

Genomic organization and gene function in Leishmania.

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7 January 2021

The unusual gene organization of Leishmania major chromosome 1 may reflect novel transcription processes

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7 January 2021

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

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7 January 2021

Mutational analysis of 3' splice site selection during trans-splicing

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7 January 2021

A common pyrimidine-rich motif governs trans-splicing and polyadenylation of tubulin polycistronic pre-mRNA in trypanosomes

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7 January 2021

Coupling of poly(A) site selection and trans-splicing in Leishmania

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7 January 2021

Regulatory sequences and a novel gene in the msp (GP63) gene cluster of Leishmania chagasi

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7 January 2021

Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi.

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7 January 2021

Developmental changes in the expression of Leishmania chagasi gp63 and heat shock protein in a human macrophage cell line.

1 reference

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7 January 2021

Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor.

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7 January 2021

Heterogeneity of the genes encoding the major surface glycoprotein of Leishmania donovani

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7 January 2021

Crithidia fasciculata contains a transcribed leishmanial surface proteinase (gp63) gene homologue.

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7 January 2021

African trypanosomes have differentially expressed genes encoding homologues of the Leishmania GP63 surface protease

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7 January 2021

Expression and Function of the Trypanosoma brucei Major Surface Protease (GP63) Genes

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7 January 2021

Differential expression of GP63 genes in Trypanosoma cruzi.

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7 January 2021

Putting the Leishmania genome to work: functional genomics by transposon trapping and expression profiling

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7 January 2021

From genomes to vaccines: Leishmania as a model

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7 January 2021

Developmental regulation of heat shock protein 83 in Leishmania. 3' processing and mRNA stability control transcript abundance, and translation id directed by a determinant in the 3'-untranslated region.

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7 January 2021

Post transcriptional control of gene expression in Leishmania.

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7 January 2021

Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63).

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7 January 2021

Stage-specific expression in Leishmania conferred by 3' untranslated regions of L. major leishmanolysin genes (GP63).

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7 January 2021

Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes.

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7 January 2021

Regulation of GP63 mRNA stability in promastigotes of virulent and attenuated Leishmania chagasi

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7 January 2021

Comparison of the post-transcriptional regulation of the mRNAs for the surface proteins PSA (GP46) and MSP (GP63) of Leishmania chagasi

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7 January 2021

Development of metacyclic Leishmania promastigotes is associated with the increasing expression of GP65, the major surface antigen

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7 January 2021

Developmental modification of the lipophosphoglycan from Leishmania major promastigotes during metacyclogenesis.

1 reference

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7 January 2021

Expression of LPG and GP63 by different developmental stages of Leishmania major in the sandfly Phlebotomus papatasi

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7 January 2021

Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan.

1 reference

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7 January 2021

Biosynthesis of the major surface protease GP63 of Leishmania chagasi

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7 January 2021

Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania

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7 January 2021

Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: implications for parasite virulence

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7 January 2021

Processing and trafficking of Leishmania mexicana GP63. Analysis using GP18 mutants deficient in glycosylphosphatidylinositol protein anchoring

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7 January 2021

Intracellular trafficking of glycosylphosphatidylinositol (GPI)-anchored proteins and free GPIs in Leishmania mexicana

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7 January 2021

GPI-anchored proteins and glycoconjugates segregate into lipid rafts in Kinetoplastida

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7 January 2021

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

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7 January 2021

Robert Feulgen Lecture 1997. Lipid microdomains and membrane trafficking in mammalian cells

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7 January 2021

Leishmania and Trypanosoma surface glycoproteins have a common glycophospholipid membrane anchor

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7 January 2021

Peptide substrate specificity of the membrane-bound metalloprotease of Leishmania

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7 January 2021

Expression and size heterogeneity of a 63 kilodalton membrane glycoprotein during growth and transformation of Leishmania mexicana amazonensis

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7 January 2021

The promastigote surface protease (gp63) of Leishmania is expressed but differentially processed and localized in the amastigote stage

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7 January 2021

Leishmania major: differential regulation of the surface metalloprotease in amastigote and promastigote stages.

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7 January 2021

The comparative fine structure and surface glycoconjugate expression of three life stages of Leishmania major

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7 January 2021

The major surface glycoprotein (GP63) is present in both life stages of Leishmania

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7 January 2021

The lysosomal gp63-related protein in Leishmania mexicana amastigotes is a soluble metalloproteinase with an acidic pH optimum

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7 January 2021

Characterisation of two soluble metalloexopeptidases in the protozoan parasite Leishmania major

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7 January 2021

Leishmania mexicana mexicana gp63 is a site-specific neutral endopeptidase

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7 January 2021

Acid protease activity of a major surface membrane glycoprotein (gp63) from Leishmania mexicana promastigotes

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7 January 2021

Substrate-dependent pH optima of gp63 purified from seven strains of Leishmania

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7 January 2021

The macrophage-attachment glycoprotein gp63 is the predominant C3-acceptor site on Leishmania mexicana promastigotes

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7 January 2021

Monoclonal antibody affinity purification of a Leishmania membrane glycoprotein and its inhibition of leishmania-macrophage binding

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7 January 2021

Phenotypic changes associated with deletion and overexpression of a stage-regulated gene family in Leishmania

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7 January 2021

Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan

1 reference

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7 January 2021

Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI):protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins.

1 reference

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7 January 2021

In vitro Leishmania major promastigote-induced macrophage migration is modulated by sensory and autonomic neuropeptides

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7 January 2021

Epitope cleavage by Leishmania endopeptidase(s) limits the efficiency of the exogenous pathway of major histocompatibility complex class I-associated antigen presentation.

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7 January 2021

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7 January 2021

Down-regulation of MARCKS-related protein (MRP) in macrophages infected with Leishmania

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7 January 2021

The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages

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7 January 2021

Migration through the extracellular matrix by the parasitic protozoan Leishmania is enhanced by surface metalloprotease gp63.

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7 January 2021

Identification of a surface metalloproteinase on 13 species of Leishmania isolated from humans, Crithidia fasciculata, and Herpetomonas samuelpessoai

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7 January 2021

Surface coat remodeling during differentiation of Trypanosoma brucei

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7 January 2021

Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2.

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7 January 2021

Analysis of antisense and double stranded RNA downregulation of A2 protein expression in Leishmania donovani

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7 January 2021

Functional analysis of cathepsin B-like cysteine proteases from Leishmania donovani complex. Evidence for the activation of latent transforming growth factor beta

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7 January 2021

Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania

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7 January 2021

Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters

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7 January 2021

Double-stranded RNA induces mRNA degradation in Trypanosoma brucei

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7 January 2021

Protozomics: trypanosomatid parasite genetics comes of age.

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7 January 2021

In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors

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7 January 2021

Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein

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7 January 2021

Cloning of the gp63 surface protease of Leishmania infantum

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7 January 2021

Leishmania panamensis: a 44bp deletion in gp63 gene is found in cDNA and genomic libraries.

1 reference

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7 January 2021

10.1016/S0166-6851(03)00211-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563532%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference