(Q35562774)

8 August 2017

title

Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells (English)

1 reference

8 August 2017

Rachael A Vaubel

1

1 reference

8 August 2017

Pierre Rustin

series ordinal

2

1 reference

8 August 2017

Grazia Isaya

series ordinal

3

1 reference

8 August 2017

language of work or name

English

0 references

publication date

19 September 2011

1 reference

Journal of Biological Chemistry

8 August 2017

published in

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8 August 2017

volume

286

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8 August 2017

issue

46

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8 August 2017

page(s)

40232-40245

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describes a project that uses

8 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3220568/fullTextXML

inferred from PubMed Central ID database lookup

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pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Human frataxin maintains mitochondrial iron homeostasis in Saccharomyces cerevisiae.

12 July 2018

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12 July 2018

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Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae

12 July 2018

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Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria

12 July 2018

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

12 July 2018

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Characterization of two site-specifically mutated human dihydrolipoamide dehydrogenases (His-452----Gln and Glu-457----Gln)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts

12 July 2018

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Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Identification of a common mutation (Gly194Cys) in both Arab Moslem and Ashkenazi Jewish patients with dihydrolipoamide dehydrogenase (E3) deficiency: possible beneficial effect of vitamin therapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Environmental stress causes oxidative damage to plant mitochondria leading to inhibition of glycine decarboxylase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

A colony color method identifies the vulnerability of mitochondria to oxidative damage

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Reduction of ubiquinone by lipoamide dehydrogenase

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.274415

Functional analysis in Saccharomyces cerevisiae of naturally occurring amino acid substitutions in human dihydrolipoamide dehydrogenase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3220568

Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase

24 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.274415

Enzyme concentrations in tissues

21 January 2018

1 reference

12 December 2020

Multifunctionality of lipoamide dehydrogenase: activities of chemically trapped monomeric and dimeric enzymes

1 reference

12 December 2020

Enhanced sensitivity of Streptomyces seoulensis to menadione by superfluous lipoamide dehydrogenase

1 reference

12 December 2020

Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae

1 reference

12 December 2020

Identification of two mutations in a compound heterozygous child with dihydrolipoamide dehydrogenase deficiency

1 reference

12 December 2020

Deficiency of dihydrolipoamide dehydrogenase due to two mutant alleles (E340K and G101del). Analysis of a family and prenatal testing

1 reference

12 December 2020

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal

1 reference

12 December 2020

Molecular basis of lipoamide dehydrogenase deficiency in Ashkenazi Jews

1 reference

12 December 2020

Lipoamide Dehydrogenase Deficiency Due to a Novel Mutation in the Interface Domain

1 reference

12 December 2020

Studies on the reaction mechanism of lipoyl dehydrogenase

1 reference

12 December 2020

Novel mutations in dihydrolipoamide dehydrogenase deficiency in two cousins with borderline-normal PDH complex activity

1 reference

12 December 2020

Studies on menadione reductase of bakers' yeast. 3. The identity of menadione reductase with lipoamide dehydrogenase

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.274415

1 reference

8 August 2017

1 reference

8 August 2017

1 reference