(Q35566370)

English

Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids

scientific article published on 3 October 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

1 reference

Europe PubMed Central

Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

0 references

1 reference

based on heuristic

inferred from title

Robert G. Salomon

object named as

Robert G Salomon

1

0 references

author name string

Li Hong

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Joe G Hollyfield

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

publication date

3 October 2011

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Chemical Research in Toxicology

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

1803-1816

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the γ-hydroxyalkenal phospholipid hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

An efficient synthesis of γ-hydroxy-α,β-unsaturated aldehydic esters of 2-lysophosphatidylcholine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.

1 reference

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12 July 2018

Signalling pathway involving GULP, MAPK and Rac1 for SR-BI-induced phagocytosis of apoptotic cells

1 reference

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DIDS protects against neuronal injury by blocking Toll-like receptor 2 activated-mechanisms

1 reference

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14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly

1 reference

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12 July 2018

Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2.

1 reference

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Integrins in angiogenesis and lymphangiogenesis

1 reference

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12 July 2018

Oxidative damage-induced inflammation initiates age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

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Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

1 reference

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12 July 2018

Complement C3 variant and the risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Functional and anatomical cortical underconnectivity in autism: evidence from an FMRI study of an executive function task and corpus callosum morphometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Modulation of atherosclerosis in mice by Toll-like receptor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Complement factor H polymorphism in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Complement factor H polymorphism and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Complement factor H variant increases the risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Functional connectivity in an fMRI working memory task in high-functioning autism

1 reference

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12 July 2018

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

RPE cells internalize low-density lipoprotein (LDL) and oxidized LDL (oxLDL) in large quantities in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity

1 reference

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12 July 2018

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

The neurobiological context of autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Locally oriented perception with intact global processing among adolescents with high-functioning autism: evidence from multiple paradigms

1 reference

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12 July 2018

Investigation of antioxidant enzymes in children with autistic disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Autism, Asperger syndrome and brain mechanisms for the attribution of mental states to animated shapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Immunological and aetiological aspects of macular degeneration

1 reference

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12 July 2018

Risk factors for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

1 reference

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12 July 2018

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Indices of lipid peroxidation in vivo: strengths and limitations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Softening of drusen and subretinal neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

12 July 2018

Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221790

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Enrichment of polyunsaturated fatty acids from rat retinal pigment epithelium to rod outer segments

1 reference

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Alterations in two enzymes: superoxide dismutase and glutathion peroxidase in developmental infantile psychosis (infantile autism) (author's transl)

1 reference

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Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

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Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes

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Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism

1 reference

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Rac1 and Toll-IL-1 receptor domain-containing adapter protein mediate Toll-like receptor 4 induction of HIV-long terminal repeat

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Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

1 reference

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26 September 2018

Oxidatively Truncated Docosahexaenoate Phospholipids: Total Synthesis, Generation, and Peptide Adduction Chemistry

1 reference

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Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.

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The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation

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A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.

1 reference

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26 September 2018

A potential role for immune complex pathogenesis in drusen formation

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Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine

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Differences in the fatty acid composition of the grey and white matter of different regions of the brains of patients with Alzheimer's disease and control subjects.

1 reference

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26 September 2018

Light-induced deposits in Bruch's membrane of protoporphyric mice

1 reference

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TLR signaling tailors innate immune responses in human microglia and astrocytes

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(Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21875030

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Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target

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https://pubmed.ncbi.nlm.nih.gov/21875030

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Docosapentaenoic acid is converted to docosahexaenoic acid in the retinas of normal and prcd-affected miniature poodle dogs

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https://pubmed.ncbi.nlm.nih.gov/21875030

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Retinal pigment epithelium possesses both LDL and scavenger receptor activity

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https://pubmed.ncbi.nlm.nih.gov/21875030

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Oxidative stress in autism

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https://pubmed.ncbi.nlm.nih.gov/21875030

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inferred from PubMed ID database lookup

Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21875030

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Immunochemical evidence supporting 2-pentylpyrrole formation on proteins exposed to 4-hydroxy-2-nonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/21875030

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Prevalence of age-related maculopathy. The Beaver Dam Eye Study

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https://pubmed.ncbi.nlm.nih.gov/21875030

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Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia

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Identifiers

10.1021/TX200206V

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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