(Q35568492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

fibrodysplasia ossificans progressiva

5 March 2020

main subject

0 references

author

Edwin G Theosmy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Andria L Culbert

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Salin A Chakkalakal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Tracy A Brennan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Frederick S Kaplan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Eileen M Shore

6

1 reference

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5 March 2020

publication date

1 May 2014

1 reference

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5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

32

1 reference

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5 March 2020

issue

5

1 reference

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5 March 2020

page(s)

1289-1300

1 reference

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describes a project that uses

5 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4419363/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva

27 July 2018

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Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification

27 July 2018

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27 July 2018

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27 July 2018

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The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization

27 July 2018

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27 July 2018

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27 July 2018

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BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

27 July 2018

1 reference

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Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1

27 July 2018

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27 July 2018

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Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP).

27 July 2018

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Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation

27 July 2018

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Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

27 July 2018

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

27 July 2018

1 reference

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Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

27 July 2018

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Craniofacial defects in mice lacking BMP type I receptor Alk2 in neural crest cells

27 July 2018

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27 July 2018

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ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development

27 July 2018

1 reference

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Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

27 July 2018

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Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

27 July 2018

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L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation

26 September 2018

1 reference

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Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.

26 September 2018

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26 September 2018

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26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Multiple functions of BMPs in chondrogenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

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26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Transcriptional Coactivator PRIP, the Peroxisome Proliferator-activated Receptor γ (PPARγ)-interacting Protein, Is Required for PPARγ-mediated Adipogenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Removal of the floxed neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo.

26 September 2018

1 reference

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The chick transcriptional repressor Nkx3.2 acts downstream of Shh to promote BMP-dependent axial chondrogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Interaction of growth factors regulating chondrocyte differentiation in the developing embryo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

The radiological spectrum of fibrodysplasia ossificans progressiva.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419363

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FSTEM.1633

The histopathology of fibrodysplasia ossificans progressiva. An endochondral process

21 January 2018

1 reference

12 December 2020

Acute lymphocytic infiltration in an extremely early lesion of fibrodysplasia ossificans progressiva

1 reference

12 December 2020

Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP)

1 reference

12 December 2020

Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold

1 reference

12 December 2020

Functional modeling of the ACVR1 (R206H) mutation in FOP

1 reference

12 December 2020

Preparation, culture, and immortalization of mouse embryonic fibroblasts

1 reference

12 December 2020

BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes

1 reference

12 December 2020

Identifiers

DOI

10.1002/STEM.1633

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

24449086

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449086%20AND%20SRC:MED&resulttype=core&format=json