(Q35573919)

8 August 2017

title

The genetics of pulmonary arterial hypertension in the post-BMPR2 era. (English)

1 reference

8 August 2017

main subject

arterial hypertension

1 reference

Joshua P Fessel

1

1 reference

8 August 2017

James E Loyd

series ordinal

2

1 reference

8 August 2017

Eric D Austin

series ordinal

3

1 reference

8 August 2017

publication date

1 July 2011

1 reference

8 August 2017

published in

Pulmonary circulation

1 reference

8 August 2017

volume

1

1 reference

8 August 2017

issue

3

1 reference

8 August 2017

page(s)

305-319

1 reference

Microarray studies in pulmonary arterial hypertension

8 August 2017

cites work

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Characterization of the vasodilatory action of testosterone in the human pulmonary circulation

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

27 July 2018

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27 July 2018

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Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

27 July 2018

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What patients and their relatives think about testing for BMPR2

27 July 2018

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Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

27 July 2018

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Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension.

27 July 2018

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Demographic features, BMPR2 status and outcomes in distal chronic thromboembolic pulmonary hypertension

27 July 2018

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Cytochrome P450 1B1-Mediated Estrogen Metabolism Results in Estrogen-Deoxyribonucleoside Adduct Formation

27 July 2018

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Genetic variation in the mitochondrial enzyme carbamyl-phosphate synthetase I predisposes children to increased pulmonary artery pressure following surgical repair of congenital heart defects: a validated genetic association study

27 July 2018

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Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

27 July 2018

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Pulmonary arterial hypertension in France: results from a national registry

27 July 2018

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Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension

27 July 2018

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Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

27 July 2018

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Repeat instability: mechanisms of dynamic mutations

27 July 2018

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Cytochrome P450-mediated metabolism of estrogens and its regulation in human.

27 July 2018

1 reference

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Comparative physiology of hypoxic pulmonary hypertension: historical clues from brisket disease

27 July 2018

1 reference

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Genetic basis of pulmonary arterial hypertension: current understanding and future directions

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

27 July 2018

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Recent studies in primary pulmonary hypertension, including pharmacodynamic observations on pulmonary vascular resistance

27 July 2018

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Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

27 July 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

27 July 2018

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Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension

27 July 2018

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BMP signaling is required for septation of the outflow tract of the mammalian heart

27 July 2018

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Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

27 July 2018

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Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

27 July 2018

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Vascular remodeling in primary pulmonary hypertension. Potential role for transforming growth factor-beta

27 July 2018

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27 July 2018

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27 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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The changing picture of patients with pulmonary arterial hypertension in the United States: how REVEAL differs from historic and non-US Contemporary Registries

26 September 2018

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Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil

26 September 2018

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26 September 2018

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Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis

26 September 2018

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Genetics and genomics of pulmonary arterial hypertension

26 September 2018

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Development and pathology of pulmonary hypertension.

26 September 2018

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Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation.

26 September 2018

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Transforming growth factor beta/bone morphogenic protein signaling in pulmonary arterial hypertension: remodeling revisited

26 September 2018

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Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension

26 September 2018

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Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease

26 September 2018

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High frequency of BMPR2 exonic deletions/duplications in familial pulmonary arterial hypertension

26 September 2018

1 reference

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SMAD4 mutations found in unselected HHT patients.

26 September 2018

1 reference

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Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Idiopathic pulmonary hypertension: what did we learn from genes?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Genetic association of the serotonin transporter in pulmonary arterial hypertension.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Gene polymorphisms of endothelial nitric oxide synthase enzyme associated with pulmonary hypertension in patients with COPD.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Prognostic factors for survival in human immunodeficiency virus-associated pulmonary arterial hypertension

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Pulmonary hypertension in scleroderma spectrum of disease: lack of bone morphogenetic protein receptor 2 mutations.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Survival in primary pulmonary hypertension: the impact of epoprostenol therapy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224422

Familial and sporadic primary pulmonary hypertension is caused by BMPR2 gene mutations resulting in haploinsufficiency of the bone morphogenetic protein tùype II receptor

15 November 2018

1 reference

12 December 2020

Angiotensin-converting enzyme gene polymorphisms and prognosis in chronic thromboembolic pulmonary hypertension

1 reference

12 December 2020

Primary pulmonary hypertension

1 reference

12 December 2020

Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension

1 reference

12 December 2020

Familial primary pulmonary hypertension: clinical patterns

1 reference

12 December 2020

Design of the REVEAL Registry for US Patients With Pulmonary Arterial Hypertension

1 reference

12 December 2020

Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines

1 reference

12 December 2020

The presence of genetic anticipation suggests that the molecular basis of familial primary pulmonary hypertension may be trinucleotide repeat expansion

1 reference

12 December 2020

Gross BMPR2 gene rearrangements constitute a new cause for primary pulmonary hypertension

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12 December 2020

Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension

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12 December 2020

Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension

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12 December 2020

Prostacyclin synthase promoter regulation and familial pulmonary arterial hypertension

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12 December 2020

Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31–32

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12 December 2020

Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension

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12 December 2020

Fine mapping of PPH1, a gene for familial primary pulmonary hypertension, to a 3-cM region on chromosome 2q33

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12 December 2020

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

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12 December 2020

The influence of sex hormones on pulmonary vascular reactivity: possible vasodilator therapies for the treatment of pulmonary hypertension

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12 December 2020

Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension

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12 December 2020

Temporal trends and drug exposures in pulmonary hypertension: an American experience

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12 December 2020

Mapping of familial primary pulmonary hypertension locus (PPH1) to chromosome 2q31-q32

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12 December 2020

Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmonary hypertension post cardiopulmonary bypass in children with congenital cardiac diseases

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12 December 2020

Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension

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12 December 2020

Primary pulmonary hypertension. I. Clinical and hemodynamic study

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12 December 2020

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

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12 December 2020

Involvement of endothelial NO in the dilator effect of VIP on rat isolated pulmonary artery

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12 December 2020

Identifiers

DOI

10.4103/2045-8932.87293

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8 August 2017

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8 August 2017

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