(Q35579544)

9 August 2017

title

Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions (English)

1 reference

9 August 2017

1 reference

ChEBI release 2020-05-28

0 references

1 reference

John T Barr

1

1 reference

9 August 2017

Jeffrey P Jones

series ordinal

2

1 reference

9 August 2017

publication date

22 September 2011

1 reference

Drug Metabolism and Disposition

9 August 2017

published in

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9 August 2017

volume

39

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9 August 2017

issue

12

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9 August 2017

page(s)

2381-2386

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Aldehyde oxidase: an enzyme of emerging importance in drug discovery

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Pharmacokinetics of a combined oral contraceptive in obese and normal-weight women

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

The effects of type II binding on metabolic stability and binding affinity in cytochrome P450 CYP3A4.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Purification and mechanism of human aldehyde oxidase expressed in Escherichia coli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Role of cytochrome P450 in drug interactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--toward a consensus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Pharmacokinetics of chlorpromazine after single and chronic dosage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

The enzyme “aldehyde oxidase” is an iminium oxidase. Reaction with nicotine Δ1′(5′) iminium ion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Increasing recognition of the importance of aldehyde oxidase in drug development and discovery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Simultaneous determination of eight estrogens and their metabolites in serum using liquid chromatography with electrochemical detection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Enzymatic oxidation of phthalazine with guinea pig liver aldehyde oxidase and liver slices: inhibition by isovanillin.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Qualitative and quantitative assessment of drug-drug interaction potential in man, based on Ki, IC50 and inhibitor concentration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Potent inhibition of human liver aldehyde oxidase by raloxifene

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Human liver aldehyde oxidase: inhibition by 239 drugs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Ziprasidone metabolism, aldehyde oxidase, and clinical implications

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

P450 interaction with HIV protease inhibitors: relationship between metabolic stability, inhibitory potency, and P450 binding spectra

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

Aldehyde oxidase-catalysed oxidation of methotrexate in the liver of guinea-pig, rabbit and man.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226377

HEPATIC ALDEHYDE OXIDASE. 3. THE SUBSTRATE-BINDING SITE

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940905

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/DMD.111.041806

1 reference

9 August 2017

1 reference

9 August 2017

1 reference