(Q35580856)

25688093

9 August 2017

title

Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly (English)

1 reference

9 August 2017

1 reference

Ignacio Pérez de Castro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Kamon Sanada

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Su Yeon Shim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Gernot Neumayer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Jian Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Sang Ki Park

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Minh Dang Nguyen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

16 February 2015

1 reference

25688093

Journal of Biological Chemistry

9 August 2017

published in

1 reference

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3 June 2020

volume

290

1 reference

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3 June 2020

issue

14

1 reference

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3 June 2020

page(s)

9122-9134

1 reference

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describes a project that uses

3 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4423697/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response

1 reference

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TPX2: of spindle assembly, DNA damage response, and cancer

27 July 2018

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Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2.

27 July 2018

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Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

27 July 2018

1 reference

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Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation

27 July 2018

1 reference

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Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells

27 July 2018

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27 July 2018

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Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

27 July 2018

1 reference

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TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

27 July 2018

1 reference

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Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome

27 July 2018

1 reference

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Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells

27 July 2018

1 reference

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The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?

27 July 2018

1 reference

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Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions

27 July 2018

1 reference

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CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.

27 July 2018

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Identification of CDK2 substrates in human cell lysates

27 July 2018

1 reference

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A quantitative atlas of mitotic phosphorylation

27 July 2018

1 reference

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Spindle pole regulation by a discrete Eg5-interacting domain in TPX2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Phosphoproteome analysis of the human mitotic spindle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Importin alpha-regulated nucleation of microtubules by TPX2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

27 July 2018

1 reference

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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

27 July 2018

1 reference

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TPX2, A novel xenopus MAP involved in spindle pole organization

27 July 2018

1 reference

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27 July 2018

The Hallmarks of Cancer

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Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

27 July 2018

1 reference

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p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M

27 July 2018

1 reference

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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

27 July 2018

1 reference

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p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

27 July 2018

1 reference

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Mitosis-specific phosphorylation of nucleolin by p34cdc2 protein kinase

27 July 2018

1 reference

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Toward a comprehensive characterization of a human cancer cell phosphoproteome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Tpx2 controls spindle integrity, genome stability, and tumor development.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Hallmarks of Cancer: The Next Generation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Control of Aurora-A stability through interaction with TPX2.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Mechanisms of chromosomal instability.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Nucleolin functions in nucleolus formation and chromosome congression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Human TPX2 is required for targeting Aurora-A kinase to the spindle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Probability-based protein identification by searching sequence databases using mass spectrometry data

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423697

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.591545

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25688093

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation ofXenopusAurora A Activation by TPX2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25688093

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.591545

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25688093%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

25688093

1 reference