(Q38189984)

30 August 2017

1 reference

title

TPX2: of spindle assembly, DNA damage response, and cancer (English)

1 reference

30 August 2017

0 references

Gernot Neumayer

1

1 reference

30 August 2017

Camille Belzil

series ordinal

2

1 reference

30 August 2017

Oliver J Gruss

series ordinal

3

1 reference

30 August 2017

Minh Dang Nguyen

series ordinal

4

1 reference

30 August 2017

language of work or name

1 reference

21 February 2014

1 reference

Cellular and Molecular Life Sciences

30 August 2017

published in

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30 August 2017

volume

71

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30 August 2017

issue

16

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30 August 2017

page(s)

3027-3047

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Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

30 August 2017

cites work

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21 January 2018

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21 January 2018

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Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies

21 January 2018

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Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization

21 January 2018

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Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display

21 January 2018

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Genes transactivated by hepatitis C virus core protein, a microarray assay

21 January 2018

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A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

21 January 2018

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Identification of a TPX2-like microtubule-associated protein in Drosophila

21 January 2018

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21 January 2018

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Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

21 January 2018

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Cell cycle. Some importin news about spindle assembly

21 January 2018

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The mechanism of spindle assembly: functions of Ran and its target TPX2

21 January 2018

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Novel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-α

21 January 2018

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The role of Hklp2 in the stabilization and maintenance of spindle bipolarity

21 January 2018

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21 January 2018

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RanGAP1 induces GTPase activity of nuclear Ras-related Ran

21 January 2018

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Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

21 January 2018

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Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

21 January 2018

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RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles

21 January 2018

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Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Transport between the cell nucleus and the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Nucleocytoplasmic transport: the soluble phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The Ran GTPase: theme and variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

21 January 2018

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The small GTPase Ran: interpreting the signs

21 January 2018

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Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Importin beta is a mitotic target of the small GTPase Ran in spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Role of importin-beta in coupling Ran to downstream targets in microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Self-organization of anastral spindles by synergy of dynamic instability, autocatalytic microtubule production, and a spatial signaling gradient

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Regulation of repp86 stability by human Siah2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Molecular requirements for kinetochore-associated microtubule formation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora-A: the maker and breaker of spindle poles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora-A and hBora join the game of Polo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Requirements for the destruction of human Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Regulation of Aurora-A kinase on the mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Control of Aurora-A stability through interaction with TPX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

HURP is part of a Ran-dependent complex involved in spindle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Proteome analysis of the human mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Uncovering new substrates for Aurora A kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The Xenopus laevis aurora/Ip11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Mitotic functions of kinesin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Human Cep192 is required for mitotic centrosome and spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Tpx2 controls spindle integrity, genome stability, and tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The plant TPX2 protein regulates prospindle assembly before nuclear envelope breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

High-resolution genomic profiles of human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

High-resolution characterization of the pancreatic adenocarcinoma genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Genetic instabilities in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Mechanisms of chromosomal instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Genomic instability--an evolving hallmark of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Pdx-1-driven overexpression of aurora a kinase induces mild ductal dysplasia of pancreatic ducts near islets in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Combined functional genome survey of therapeutic targets for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Microtubules as a target for anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Short exposure to paclitaxel induces multipolar spindle formation and aneuploidy through promotion of acentrosomal pole assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Selective killing of cancer cells by Ashwagandha leaf extract and its component Withanone involves ROS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Living on a break: cellular senescence as a DNA-damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Examination of the expanding pathways for the regulation of p21 expression and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Crosstalk between histone modifications during the DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Integrated cross-species transcriptional network analysis of metastatic susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

DNA damage signaling in response to double-strand breaks during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Constitutive expression of γ-H2AX has prognostic relevance in triple negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

An oncogene-induced DNA damage model for cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

21 January 2018

Giant cell tumor of bone

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora A moonlights in neurite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Cortical progenitor expansion, self-renewal and neurogenesis-a polarized perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Spindle regulation in neural precursors of flies and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Ndel1 promotes axon regeneration via intermediate filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Interkinetic nuclear migration: cell cycle on the move

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Guiding neuronal cell migrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Protein database searches using compositionally adjusted substitution matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of gene markers associated with aggressive meningioma by filtering across multiple sets of gene expression arrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

repp86 Expression and Outcome in Patients With Neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Malignancy in giant cell tumor of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Restricted-Expressed Proliferation–Associated Protein (Repp86) Expression in Squamous Cell Carcinoma of the Oral Cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1582-7

Degradation of human Aurora-A protein kinase is mediated by hCdh1

21 January 2018

1 reference

12 December 2020

Expression of γ-H2AX in endometrial carcinomas: an immunohistochemical study with p53

1 reference

12 December 2020

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

1 reference

12 December 2020

repp86: A human protein associated in the progression of mitosis

1 reference

12 December 2020

Determinants for Aurora-A activation and Aurora-B discrimination by TPX2.

1 reference

12 December 2020

Stay tuned for some importin news about spindle assembly

1 reference

12 December 2020

The Aurora kinase family in cell division and cancer.

1 reference

12 December 2020

Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies

1 reference

12 December 2020

Ndel1 controls the dynein-mediated transport of vimentin during neurite outgrowth

1 reference

12 December 2020

The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?

1 reference

12 December 2020

p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M

1 reference

12 December 2020

Potential molecular marker for detecting transitional cell carcinoma

1 reference

12 December 2020

Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication

1 reference

12 December 2020

Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time

1 reference

12 December 2020

The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations.

1 reference

12 December 2020

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

1 reference

12 December 2020

The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5

1 reference

12 December 2020

A novel mechanism for activation of the protein kinase Aurora A

1 reference

12 December 2020

Prognostic significance of hepatoma-up-regulated protein expression in patients with urinary bladder transitional cell carcinoma

1 reference

12 December 2020

Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve

1 reference

12 December 2020

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

1 reference

12 December 2020

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

12 December 2020

The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer

1 reference

12 December 2020

Expression of TPX2 in salivary gland carcinomas.

1 reference

12 December 2020

Prognostic significance of a novel proliferation marker, anti-repp 86, for endometrial carcinoma: a multivariate study

1 reference

12 December 2020

Biology of Aurora A kinase: implications in cancer manifestation and therapy

1 reference

12 December 2020

[Expression and clinical significance of hepatocellular cancer antigen genes in human hepatocellular carcinoma].

1 reference

12 December 2020

10.1007/S00018-014-1582-7

Identifiers

DOI

1 reference

30 August 2017

1 reference