(Q35582328)

9 August 2017

1 reference

reason for preferred rank

title

Regulation of Pancreatic .BETA.-cell Function by the HNF Transcription Network: Lessons from Maturity-Onset Diabetes of the Young (MODY) (English)

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

1 April 2024

Regulation of pancreatic beta-cell function by the HNF transcription network: lessons from maturity-onset diabetes of the young (MODY) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14614204

maturity-onset diabetes of the young

1 April 2024

main subject

1 reference

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14614204

1 April 2024

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

1 April 2024

author name string

Kazuya Yamagata

1

1 reference

9 August 2017

language of work or name

1 reference

1 October 2003

1 reference

9 August 2017

1 reference

9 August 2017

50

1 reference

9 August 2017

491-499

1 reference

9 August 2017

5

1 reference

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

9 August 2017

1

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

1 April 2024

2

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.

1 April 2024

3

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

1 April 2024

4

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

1 April 2024

5

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas

1 April 2024

6

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors

1 April 2024

7

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.

1 April 2024

8

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Sleep apnea causes daytime hypertension

1 April 2024

9

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

1 April 2024

10

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization

1 April 2024

12

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Structure/function studies of hepatocyte nuclear factor-1alpha, a diabetes-associated transcription factor

1 April 2024

13

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Identification of mutations in the hepatocyte nuclear factor (HNF)-1 alpha gene in Japanese subjects with IDDM

1 April 2024

14

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community

1 April 2024

15

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutations in the hepatocyte nuclear factor-1alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM.

1 April 2024

16

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutations in the hepatocyte nuclear factor-1alpha gene (MODY3) are not a major cause of late-onset NIDDM in Japanese subjects

1 April 2024

17

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.

1 April 2024

18

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

1 April 2024

19

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

1 April 2024

20

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

1 April 2024

21

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.

1 April 2024

22

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta

1 April 2024

23

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction

1 April 2024

24

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.

1 April 2024

25

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatocyte nuclear factor-1alpha modulates pancreatic beta-cell growth by regulating the expression of insulin-like growth factor-1 in INS-1 cells

1 April 2024

26

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice

1 April 2024

27

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

A transcription factor regulatory circuit in differentiated pancreatic cells

1 April 2024

28

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

1 April 2024

29

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

1 April 2024

30

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

1 April 2024

31

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young

1 April 2024

32

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function

1 April 2024

33

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Maturity-onset diabetes of the young due to a mutation in the hepatocyte nuclear factor-4 alpha binding site in the promoter of the hepatocyte nuclear factor-1 alpha gene

1 April 2024

34

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels

1 April 2024

35

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

T130I mutation in HNF-4alpha gene is a loss-of-function mutation in hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjects

1 April 2024

36

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

1 April 2024

37

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

1 April 2024

38

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 April 2024

39

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

1 April 2024

40

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Identification of a gain-of-function mutation in the HNF-1beta gene in a Japanese family with MODY.

1 April 2024

43

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

The mutated human gene encoding hepatocyte nuclear factor 1beta inhibits kidney formation in developing Xenopus embryos

1 April 2024

44

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Thyroid hormone receptor interacting protein 3 (trip3) is a novel coactivator of hepatocyte nuclear factor-4alpha.

1 April 2024

45

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

R127W-HNF-4alpha is a loss of function mutation but not a rare polymorphism and causes Type II diabetes in a Japanese family with MODY1.

1 April 2024

46

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

1 April 2024

47

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 April 2024

49

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Identification of missense mutations in the hepatocyte nuclear factor-3beta gene in Japanese subjects with late-onset Type II diabetes mellitus

1 April 2024

50

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Mutation screening of the hepatocyte nuclear factor (HNF)-6 gene in Japanese subjects with diabetes mellitus

1 April 2024

51

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion

1 April 2024

52

1 reference

https://api.crossref.org/works/10.1507/ENDOCRJ.50.491

1 April 2024

Identifiers

1 reference

9 August 2017

1 reference