(Q35582384)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome (English)

1 reference

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6 March 2020

0 references

3

1 reference

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6 March 2020

author name string

Wesley K Kroeze

1

1 reference

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6 March 2020

Maria F Sassano

2

1 reference

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6 March 2020

Katherine Lansu

4

1 reference

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6 March 2020

John D McCorvy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Patrick M Giguère

6

1 reference

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6 March 2020

Noah Sciaky

7

1 reference

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6 March 2020

Bryan L Roth

8

1 reference

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6 March 2020

publication date

20 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

6 March 2020

published in

1 reference

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6 March 2020

volume

22

1 reference

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6 March 2020

issue

5

1 reference

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6 March 2020

page(s)

362-369

1 reference

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https://scigraph.springernature.com/pub.10.1038/nsmb.3014

6 March 2020

exact match

0 references

cites work

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12 July 2018

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Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist

12 July 2018

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Identification of novel functionally selective κ-opioid receptor scaffolds

12 July 2018

1 reference

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The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

12 July 2018

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The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.

12 July 2018

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Structural Features for Functional Selectivity at Serotonin Receptors

12 July 2018

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Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors

12 July 2018

1 reference

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Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK.

12 July 2018

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Structure of the human κ-opioid receptor in complex with JDTic

12 July 2018

1 reference

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Diversity and modularity of G protein-coupled receptor structures

12 July 2018

1 reference

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Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy

12 July 2018

1 reference

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12 July 2018

Too many roads not taken

1 reference

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Insights into GPCR pharmacology from the measurement of changes in intracellular cyclic AMP; advantages and pitfalls of differing methodologies

12 July 2018

1 reference

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Strategies to discover unexpected targets for drugs active at G protein-coupled receptors

12 July 2018

1 reference

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Predicting new molecular targets for known drugs

12 July 2018

1 reference

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A homogeneous fluorescent live-cell assay for measuring 7-transmembrane receptor activity and agonist functional selectivity through beta-arrestin recruitment

12 July 2018

1 reference

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Using reporter gene technologies to detect changes in cAMP as a result of GPCR activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424118

Beta-arrestin-based Bret2 screening assay for the "non"-beta-arrestin binding CB1 receptor

12 July 2018

1 reference

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Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression

12 July 2018

1 reference

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A specific mechanism for nonspecific activation in reporter-gene assays

12 July 2018

1 reference

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Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50

12 July 2018

1 reference

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Characterization of chemical libraries for luciferase inhibitory activity

12 July 2018

1 reference

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The genetic design of signaling cascades to record receptor activation

12 July 2018

1 reference

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Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and beta-arrestin interaction

12 July 2018

1 reference

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Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening

12 July 2018

1 reference

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Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells.

12 July 2018

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Novel GPCR screening approach: indirect identification of S1P receptor agonists in antagonist screening using a calcium assay

12 July 2018

1 reference

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Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors

12 July 2018

1 reference

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Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

12 July 2018

1 reference

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Differential beta-arrestin binding of AT1 and AT2 angiotensin receptors.

12 July 2018

1 reference

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Transduction of receptor signals by beta-arrestins

12 July 2018

1 reference

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Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes

12 July 2018

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Cell-Based High-Throughput Screening Assay System for Monitoring G Protein-Coupled Receptor Activation Using β-Galactosidase Enzyme Complementation Technology

12 July 2018

1 reference

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Analysis of the Coupling of G<SUB>12/13</SUB> to G Protein-Coupled Receptors Using a Luciferase Reporter Assay

12 July 2018

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The G protein-coupled receptor repertoires of human and mouse

12 July 2018

1 reference

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12 July 2018

1 reference

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Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation

12 July 2018

1 reference

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Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

12 July 2018

1 reference

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Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors

12 July 2018

1 reference

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Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells

12 July 2018

1 reference

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A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

12 July 2018

1 reference

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Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

12 July 2018

1 reference

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Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide

12 July 2018

1 reference

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NOBEL 2012 Chemistry: Studies of a ubiquitous receptor family.

12 July 2018

1 reference

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Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424118

The repertoire of G-protein-coupled receptors in fully sequenced genomes

26 September 2018

1 reference

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Agonism, inverse agonism, and neutral antagonism at the constitutively active human neurotensin receptor 2.

26 September 2018

1 reference

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Screening G protein-coupled receptors: measurement of intracellular calcium using the fluorometric imaging plate reader

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.3014

Safety of nateglinide as used in general practice in England: results of a prescription-event monitoring study

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.3014

31 March 2020

Identifiers

DOI

10.1038/NSMB.3014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25895059

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25895059%20AND%20SRC:MED&resulttype=core&format=json