(Q35582990)

9 August 2017

1 reference

title

Heparan sulfate core proteins in cell-cell signaling (English)

1 reference

9 August 2017

Heparan Sulfate Core Proteins in Cell-Cell Signaling (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

1 April 2024

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

1 April 2024

author name string

Kenneth L. Kramer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14616070

1 April 2024

H. Joseph Yost

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14616070

1 April 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14616070

1 April 2024

publication date

1 January 2003

1 reference

full work available at URL

9 August 2017

https://www.annualreviews.org/doi/pdf/10.1146/annurev.genet.37.061103.090226

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Annual Review of Genetics

1 April 2024

published in

1 reference

9 August 2017

volume

37

1 reference

9 August 2017

page(s)

461-484

1 reference

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

9 August 2017

cites work

1 reference

1 April 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NCB797

Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice

1

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition

1 April 2024

2

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta

1 April 2024

3

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Self-association of N-Syndecan (Syndecan-3) Core Protein Is Mediated by a Novel Structural Motif in the Transmembrane Domain and Ectodomain Flanking Region

1 April 2024

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1 April 2024

7

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor

1 April 2024

8

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Functions of cell surface heparan sulfate proteoglycans

1 April 2024

9

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC

1 April 2024

11

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling

1 April 2024

12

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

1 April 2024

13

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

1 April 2024

14

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors

1 April 2024

15

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

1 April 2024

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome

1 April 2024

17

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells

1 April 2024

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

1 April 2024

21

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Betaglycan inhibits TGF-beta signaling by preventing type I-type II receptor complex formation. Glycosaminoglycan modifications alter betaglycan function

1 April 2024

22

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Order out of chaos: assembly of ligand binding sites in heparan sulfate

1 April 2024

23

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Ligand binding and functional properties of betaglycan, a co-receptor of the transforming growth factor-beta superfamily. Specialized binding regions for transforming growth factor-beta and inhibin A

1 April 2024

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Synbindin, A novel syndecan-2-binding protein in neuronal dendritic spines

1 April 2024

25

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

EphB/syndecan-2 signaling in dendritic spine morphogenesis

1 April 2024

26

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons

1 April 2024

27

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase

1 April 2024

28

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling

1 April 2024

29

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of Drosophila

1 April 2024

30

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Dally regulates Dpp morphogen gradient formation in the Drosophila wing.

1 April 2024

31

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration

1 April 2024

32

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient

1 April 2024

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

UDP-sugar transporter implicated in glycosylation and processing of Notch

1 April 2024

35

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecans in inflammation

1 April 2024

36

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Characterization of the heparan sulfate and chondroitin sulfate assembly sites in CD44

1 April 2024

38

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis

1 April 2024

39

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes

1 April 2024

40

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syntenin, a PDZ protein that binds syndecan cytoplasmic domains

1 April 2024

41

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

1 April 2024

43

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties

1 April 2024

44

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine

1 April 2024

45

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis

1 April 2024

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Fibroblast growth factor-specific modulation of cellular response by syndecan-4

1 April 2024

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2

1 April 2024

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Cerebroglycan, a developmentally regulated cell-surface heparan sulfate proteoglycan, is expressed on developing axons and growth cones

1 April 2024

52

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Spatiotemporal distribution of heparan sulfate epitopes during myogenesis and synaptogenesis: a study in developing mouse intercostal muscle

1 April 2024

54

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory

1 April 2024

55

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

1 April 2024

56

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

PKCgamma regulates syndecan-2 inside-out signaling during xenopus left-right development.

1 April 2024

57

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor

1 April 2024

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth

1 April 2024

59

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Do morphogen gradients arise by diffusion?

1 April 2024

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Betaglycan binds inhibin and can mediate functional antagonism of activin signalling

1 April 2024

63

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

1 April 2024

64

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1 April 2024

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice

1 April 2024

68

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Cell-free synthesis of anticoagulant heparan sulfate reveals a limiting converting activity that modifies an excess precursor pool

1 April 2024

69

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities

1 April 2024

70

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

1 April 2024

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Betaglycan presents ligand to the TGF beta signaling receptor.

1 April 2024

72

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

1 April 2024

73

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Identification of an adhesion site within the syndecan-4 extracellular protein domain

1 April 2024

74

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Characterization of the high affinity cell-binding domain in the cell surface proteoglycan syndecan-4

1 April 2024

75

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

EXT gene family member rib-2 is essential for embryonic development and heparan sulfate biosynthesis in Caenorhabditis elegans

1 April 2024

76

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.

1 April 2024

79

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

1 April 2024

80

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Tyrosine phosphorylation of syndecan-1 and -4 cytoplasmic domains in adherent B82 fibroblasts

1 April 2024

81

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development

1 April 2024

82

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence

1 April 2024

83

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Producing cells retain and recycle Wingless in Drosophila embryos.

1 April 2024

84

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo

1 April 2024

86

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

CD44: from adhesion molecules to signalling regulators

1 April 2024

87

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity

1 April 2024

88

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Molecular interactions of syndecans during development

1 April 2024

89

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.

1 April 2024

90

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3.

1 April 2024

92

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

P62 association with RNA is regulated by tyrosine phosphorylation.

1 April 2024

93

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Roles of heparan-sulphate glycosaminoglycans in cancer

1 April 2024

95

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain

1 April 2024

96

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

1 April 2024

97

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events

1 April 2024

98

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth

1 April 2024

99

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

1 April 2024

100

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecan-4-mediated signalling

1 April 2024

102

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases

1 April 2024

103

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

The role of glypicans in mammalian development

1 April 2024

104

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse

1 April 2024

107

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Embryonic expression patterns of Xenopus syndecans

1 April 2024

108

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Clustering induces redistribution of syndecan-4 core protein into raft membrane domains

1 April 2024

109

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension

1 April 2024

110

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo

1 April 2024

112

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1 April 2024

113

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

1 April 2024

114

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Morphogen transport along epithelia, an integrated trafficking problem

1 April 2024

115

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish.

1 April 2024

116

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Inhibin is an antagonist of bone morphogenetic protein signaling

1 April 2024

117

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion component

1 April 2024

118

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecan-4 and focal adhesion function

1 April 2024

119

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

A new strategy for defining critical functional groups on heparan sulfate

1 April 2024

120

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

The involvement of heparan sulfate (HS) in FGF1/HS/FGFR1 signaling complex

1 April 2024

121

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1

1 April 2024

122

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Glycobiology of the synapse: the role of glycans in the formation, maturation, and modulation of synapses

1 April 2024

123

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1 April 2024

124

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans

1 April 2024

125

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7)

1 April 2024

126

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling

1 April 2024

127

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Syndecan-1 and -4 synthesized simultaneously by mouse mammary gland epithelial cells bear heparan sulfate chains that are apparently structurally indistinguishable

1 April 2024

129

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Amino acid determinants that drive heparan sulfate assembly in a proteoglycan

1 April 2024

130

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

Membrane heparan sulfate proteoglycan-supported FGF2-FGFR1 signaling: evidence in support of the "cooperative end structures" model.

1 April 2024

131

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.GENET.37.061103.090226

1 April 2024

Identifiers

1 reference

9 August 2017

1 reference