(Q35590264)

9 August 2017

title

Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs (English)

1 reference

9 August 2017

1 reference

4

Jeffrey V Ravetch

1 reference

9 August 2017

Benjamin M Fiebiger

1

1 reference

9 August 2017

Jad Maamary

series ordinal

2

1 reference

9 August 2017

Andrew Pincetic

series ordinal

3

1 reference

9 August 2017

language of work or name

English

0 references

publication date

13 April 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

112

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9 August 2017

issue

18

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9 August 2017

page(s)

E2385-94

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IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells

9 August 2017

cites work

1 reference

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IL-33 attenuates the development of experimental autoimmune uveitis.

12 July 2018

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Type I and type II Fc receptors regulate innate and adaptive immunity

12 July 2018

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The alarmin IL-33 promotes regulatory T-cell function in the intestine

12 July 2018

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Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins

12 July 2018

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Intravenous immunoglobulin-induced IL-33 is insufficient to mediate basophil expansion in autoimmune patients

12 July 2018

1 reference

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Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils.

12 July 2018

1 reference

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T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.

12 July 2018

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Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies

12 July 2018

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General mechanism for modulating immunoglobulin effector function

12 July 2018

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Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

12 July 2018

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Tregitope update: mechanism of action parallels IVIg

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Analysis and functional consequences of increased Fab-sialylation of intravenous immunoglobulin (IVIG) after lectin fractionation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

The role of sialic acid as a modulator of the anti-inflammatory activity of IgG.

12 July 2018

1 reference

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Intravenous immunoglobulin expands regulatory T cells in autoimmune rheumatic disease

12 July 2018

1 reference

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Novel roles for the IgG Fc glycan

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

12 July 2018

1 reference

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Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Potential application of tregitopes as immunomodulating agents in multiple sclerosis

12 July 2018

1 reference

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Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.

12 July 2018

1 reference

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Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Antibody-mediated modulation of immune responses.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

A novel role for the IgG Fc glycan: the anti-inflammatory activity of sialylated IgG Fcs.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcgammaRIII+ phagocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Identification of a receptor required for the anti-inflammatory activity of IVIG.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

12 July 2018

1 reference

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A mechanism for the initiation of allergen-induced T helper type 2 responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Th17 cells: effector T cells with inflammatory properties

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Primary immunodeficiency disorders: antibody deficiency

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Intravenous immunoglobulin attenuates airway inflammation through induction of forkhead box protein 3-positive regulatory T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Interleukin-33 prolongs allograft survival during chronic cardiac rejection.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Intravenous immunoglobulin therapy affects T regulatory cells by increasing their suppressive function.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Active induction of experimental allergic encephalomyelitis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426441

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

26 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1505292112

Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1505292112

Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1505292112

Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1505292112

Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1505292112

Interleukin-33 augments Treg cell levels: a flaw mechanism in atherosclerosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25870292

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1505292112

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference