(Q35597474)

9 August 2017

title

Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells (English)

1 reference

9 August 2017

Jing Liang

1

1 reference

9 August 2017

Tan Li

2

1 reference

9 August 2017

Ya-Li Zhang

3

1 reference

9 August 2017

Zong-Lou Guo

4

1 reference

9 August 2017

Li-Hong Xu

5

1 reference

9 August 2017

publication date

1 December 2011

1 reference

Journal of Zhejiang University. Science. B

9 August 2017

published in

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9 August 2017

volume

12

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9 August 2017

issue

12

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9 August 2017

page(s)

951-960

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A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence

9 August 2017

cites work

1 reference

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Identification of temporal differentially expressed protein responses to microcystin in human amniotic epithelial cells

12 July 2018

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Hormesis: why it is important to toxicology and toxicologists

12 July 2018

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Alteration of proteins expression in apoptotic FL cells induced by MCLR.

12 July 2018

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Expression of protein phosphatase 2A mutants and silencing of the regulatory B alpha subunit induce a selective loss of acetylated and detyrosinated microtubules

12 July 2018

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Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.

12 July 2018

1 reference

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Structure of the protein phosphatase 2A holoenzyme

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

12 July 2018

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Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins

12 July 2018

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dUTP Pyrophosphatase, its appearance in extracellular compartment may serve as a potential biomarker for N-methyl-N'-nitro-N-nitrosoguanidine exposure in mammalian cells

12 July 2018

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Proteomic profiling for cellular responses to different concentrations of N-methyl-N'-nitro-N-nitrosoguanidine

12 July 2018

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Identification of specific PP2A complexes involved in human cell transformation

12 July 2018

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Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.

12 July 2018

1 reference

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Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases

12 July 2018

1 reference

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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

12 July 2018

1 reference

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Applications of hormesis in toxicology, risk assessment and chemotherapeutics

12 July 2018

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HDAC6 is a microtubule-associated deacetylase

12 July 2018

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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

12 July 2018

1 reference

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Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Microcystins (cyanobacterial toxins) in drinking water enhance the growth of aberrant crypt foci in the mouse colon

12 July 2018

1 reference

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Microcystic cyanobacteria extract induces cytoskeletal disruption and intracellular glutathione alteration in hepatocytes

12 July 2018

1 reference

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Enhancement of glutathione S-transferase placental-form positive liver cell foci development by microcystin-LR in aflatoxin B1-initiated rats.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Autoregulation of protein phosphatase type 2A expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Neoplastic nodular formation in mouse liver induced by repeated intraperitoneal injections of microcystin-LR.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Primary prevention of hepatocellular carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Protein phosphatase inhibitors induce the selective breakdown of stable microtubules in fibroblasts and epithelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Inhibition of protein phosphatases by microcystins and nodularin associated with hepatotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

The apoptotic effect of oral administration of microcystin-RR on mice liver

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

In vivo study on the effects of microcystin extracts on the expression profiles of proto-oncogenes (c-fos, c-jun and c-myc) in liver, kidney and testis of male Wistar rats injected i.v. with toxins.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Hepatic gene expression changes in mice associated with prolonged sublethal microcystin exposure.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Induced endoplasmic reticulum (ER) stress and binding of over-expressed ER specific chaperone GRP78/BiP with dimerized epidermal growth factor receptor in mammalian cells exposed to low concentration of N-methyl-N'-nitro-N-nitrosoguanidine

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Toxic cyanobacteria and microcystin concentrations in a public water supply reservoir in the Brazilian Amazonia region.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Occurrence and elimination of cyanobacterial toxins in drinking water treatment plants

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Antioxidant enzyme activity and lipid peroxidation in liver and kidney of rats exposed to microcystin-LR administered intraperitoneally.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Continuous cultivation of epithelial cell strain (FL) from human amniotic membrane.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Toxic effects of microcystins in the hepatopancreas of the estuarine crab Chasmagnathus granulatus (Decapoda, Grapsidae).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Hepatic accumulation and effects of microcystin-LR on juvenile goldfish Carassius auratus L.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

The expression of bcl-2 and bax genes during microcystin induced liver tumorigenesis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Studies on oxidative damage induced by cyanobacteria extract in primary cultured rat hepatocytes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Protein phosphatases independently regulate vesicle movement and microtubule subpopulations in hepatocytes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Characterization of chemically tritiated microcystin-LR and its distribution in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232427

Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin-induced rapid apoptosis in rat hepatocytes

26 September 2018

1 reference

12 December 2020

Potent cytotoxicity of the phosphatase inhibitor microcystin LR and microcystin analogues in OATP1B1- and OATP1B3-expressing HeLa cells

1 reference

12 December 2020

Oral administration of cyanobacterial bloom extract induced the altered expression of the PP2A, Bax, and Bcl-2 in mice

1 reference

12 December 2020

Liver failure and death after exposure to microcystins at a hemodialysis center in Brazil

1 reference

12 December 2020

The cyanobacterial toxin, microcystin-LR, can induce apoptosis in a variety of cell types

1 reference

12 December 2020

Induction of apoptosis in mouse liver by microcystin-LR: a combined transcriptomic, proteomic, and simulation strategy

1 reference

12 December 2020

Altered expression of p53, Bcl-2 and Bax induced by microcystin-LR in vivo and in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1631/JZUS.B1100121

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Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

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