(Q48654126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

S E Merrick

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

J Q Trojanowski

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

V M Lee

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 August 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

published in

Journal of Neuroscience

1 reference

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4 November 2019

volume

17

1 reference

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4 November 2019

issue

15

1 reference

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4 November 2019

page(s)

5726-5737

1 reference

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describes a project that uses

4 November 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6573204/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Individual microtubules in the axon consist of domains that differ in both composition and stability

1 reference

12 December 2020

Stabilization of post-translational modification of microtubules during cellular morphogenesis

1 reference

12 December 2020

Phosphorylation affects the ability of tau protein to promote microtubule assembly.

1 reference

12 December 2020

Rapid changes in the distribution of GAP-43 correlate with the expression of neuronal polarity during normal development and under experimental conditions

1 reference

12 December 2020

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo.

1 reference

12 December 2020

Site-specific phosphorylation of the middle molecular weight human neurofilament protein in transfected non-neuronal cells

1 reference

12 December 2020

NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell

1 reference

12 December 2020

p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

1 reference

12 December 2020

Neurofilament-associated protein phosphatase 2A: its possible role in preserving neurofilaments in filamentous states.

1 reference

12 December 2020

An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues

1 reference

12 December 2020

Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms

1 reference

12 December 2020

cdc2 kinase-induced destabilization of MAP2-coated microtubules in Xenopus egg extracts.

1 reference

12 December 2020

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

1 reference

12 December 2020

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

12 December 2020

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

1 reference

12 December 2020

In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

1 reference

12 December 2020

Association of tau protein with microtubules in living cells

1 reference

12 December 2020

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

1 reference

12 December 2020

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

12 December 2020

Epitopes that span the tau molecule are shared with paired helical filaments.

1 reference

12 December 2020

Selective stabilization of microtubules oriented toward the direction of cell migration

1 reference

12 December 2020

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

1 reference

12 December 2020

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture

1 reference

12 December 2020

Mapping of the Alz 50 epitope in microtubule-associated proteins tau

1 reference

12 December 2020

Light and electron microscopic studies of the distribution of microtubule-associated protein 2 in rat brain: a difference between dendritic and axonal cytoskeletons

1 reference

12 December 2020

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

12 December 2020

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau

1 reference

12 December 2020

Calyculin A and okadaic acid: inhibitors of protein phosphatase activity

1 reference

12 December 2020

Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins.

1 reference

12 December 2020

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

1 reference

12 December 2020

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

12 December 2020

Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

1 reference

12 December 2020

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

1 reference

12 December 2020

Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

1 reference

12 December 2020

Expression of microtubule-associated protein 2 by reactive astrocytes

1 reference

12 December 2020

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line

1 reference

12 December 2020

Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent tau and accumulation of abnormal tau-isoforms (A68 proteins)

1 reference

12 December 2020

10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin

1 reference

12 December 2020

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

1 reference

12 December 2020

Okadaic acid: a new probe for the study of cellular regulation

1 reference

12 December 2020

Promotion of microtubule assembly in vitro by taxol

1 reference

12 December 2020

Posttranslational modification and microtubule stability

1 reference

12 December 2020

A protein factor essential for microtubule assembly

1 reference

12 December 2020

Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level

1 reference

12 December 2020

A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs).

1 reference

12 December 2020

Microtubule dynamics in axons and dendrites

1 reference

12 December 2020

Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain

1 reference

12 December 2020

Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro

1 reference

12 December 2020

Protein phosphatase inhibitors induce the selective breakdown of stable microtubules in fibroblasts and epithelial cells

1 reference

12 December 2020

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1 reference

12 December 2020

Microtubules containing detyrosinated tubulin are less dynamic

1 reference

12 December 2020

Assembly and turnover of detyrosinated tubulin in vivo

1 reference

12 December 2020

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

12 December 2020

Differential turnover of tyrosinated and detyrosinated microtubules

1 reference

12 December 2020

Tubulin dynamics in cultured mammalian cells

1 reference

12 December 2020

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

1 reference

12 December 2020

Distribution of tau proteins in the normal human central and peripheral nervous system

1 reference

12 December 2020

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid

1 reference

12 December 2020

10.1523/JNEUROSCI.17-15-05726.1997

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9221771%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

9221771

1 reference