(Q35597943)

9 August 2017

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title

Targeting the over-expressed urokinase-type plasminogen activator receptor on glioblastoma multiforme (English)

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9 August 2017

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5

Daniel A Vallera

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9 August 2017

Edward Rustamzadeh

1

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9 August 2017

Chunbin Li

series ordinal

2

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9 August 2017

Sekou Doumbia

series ordinal

3

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9 August 2017

Walter A Hall

series ordinal

4

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9 August 2017

publication date

1 October 2003

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Journal of Neuro-Oncology

9 August 2017

published in

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9 August 2017

volume

65

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9 August 2017

issue

1

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9 August 2017

page(s)

63-75

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Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma.

9 August 2017

cites work

1 reference

12 December 2020

Local application of radiolabeled monoclonal antibodies in the treatment of high grade malignant gliomas: a six-year clinical experience.

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12 December 2020

Radiation-induced autophosphorylation of epidermal growth factor receptor in human malignant mammary and squamous epithelial cells.

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12 December 2020

Prevention of metastasis by inhibition of the urokinase receptor

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12 December 2020

Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms

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12 December 2020

The cost effectiveness of stereotactic radiosurgery versus surgical resection in the treatment of solitary metastatic brain tumors

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12 December 2020

Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery

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12 December 2020

The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling

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12 December 2020

Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent.

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12 December 2020

Glioblastoma multiforme; review of 219 cases with regard to natural history, pathology, diagnostic methods, and treatment

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12 December 2020

Cognitive outcomes and long-term follow-up results after enhanced chemotherapy delivery for primary central nervous system lymphoma.

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12 December 2020

Pre-radiation chemotherapy for malignant glioma in adults

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12 December 2020

Interstitial fluid pressure in DMBA-induced rat mammary tumours

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12 December 2020

Immunotoxins for central nervous system malignancy

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12 December 2020

Cloned fragment of diphtheria toxin linked to T cell-specific antibody identifies regions of B chain active in cell entry

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12 December 2020

Efficacy after sequencing of brain radiotherapy and enhanced antibody targeted chemotherapy delivery in a rodent human lung cancer brain xenograft model

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12 December 2020

Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates

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12 December 2020

Protein content and enzymatic assays of interstitial fluid from some normal tissues and transplanted mouse tumors

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12 December 2020

Molecular modification of a recombinant anti-CD3epsilon-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model

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12 December 2020

Epidemiology of brain tumors: the national survey of intracranial neoplasms

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12 December 2020

Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means

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12 December 2020

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

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12 December 2020

Diagnostic yield in CT-guided stereotactic biopsy of gliomas.

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12 December 2020

Basic fibroblast growth factor-Pseudomonas exotoxin chimeric proteins; comparison with acidic fibroblast growth factor-Pseudomonas exotoxin.

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12 December 2020

Immunotoxins: hybrid molecules combining high specificity and potent cytotoxicity

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12 December 2020

A pilot study of monoclonal antibody targeted radiotherapy in the treatment of central nervous system leukaemia in children

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12 December 2020

Targeting the tumor vasculature: inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate

1 reference

12 December 2020

Treatment of recurrent and cystic malignant gliomas by a single intracavity injection of 131I monoclonal antibody: feasibility, pharmacokinetics and dosimetry

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12 December 2020

Immunotoxins for brain tumor therapy.

1 reference

12 December 2020

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12 December 2020

Interleukin-13 receptor as a unique target for anti-glioblastoma therapy

1 reference

12 December 2020

Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice

1 reference

12 December 2020

Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa

1 reference

12 December 2020

Synergistic effect of ricin in combination with daunorubicin, cis-dichlorodiammineplatinum(II) and vincristine in systemic L1210 leukemia.

1 reference

12 December 2020

Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells.

1 reference

12 December 2020

Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells

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12 December 2020

Use of immunotoxin to inhibit proliferating human corneal endothelium

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12 December 2020

Local treatment of brain tumors with targeted chimera cytotoxic proteins

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12 December 2020

Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms.

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12 December 2020

The amino-terminal fragment of human urokinase directs a recombinant chimeric toxin to target cells: internalization is toxin mediated.

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12 December 2020

Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection

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12 December 2020

Historic milestones in cancer biology: a few that are important in cancer treatment (revisited)

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12 December 2020

An immune regulatory cytokine receptor and glioblastoma multiforme: an unexpected link

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12 December 2020

Drug resistance and cancer

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12 December 2020

Immunotoxins and central nervous system neoplasia

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12 December 2020

Overexpressed cell surface interleukin-4 receptor molecules can be successfully targeted for antitumor cytotoxin therapy

1 reference

12 December 2020

Infiltration of the leptomeninges by systemic cancer. A clinical and pathologic study

1 reference

12 December 2020

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors

1 reference

12 December 2020

Pharmacokinetics, tissue distribution, and in vivo antitumor effects of the antimelanoma immunotoxin ZME-gelonin

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12 December 2020

Systemic chemotherapy of brain metastases from small-cell lung cancer: a review

1 reference

12 December 2020

Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells

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12 December 2020

Collagenolytic mechanisms in tumor cell invasion

1 reference

12 December 2020

A quantitative analysis of tumor specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels

1 reference

12 December 2020

Components of the plasminogen activation system in uveal melanoma—a clinico-pathological study

1 reference

12 December 2020

Efficacy of transferrin receptor-targeted immunotoxins in brain tumor cell lines and pediatric brain tumors

1 reference

12 December 2020

National survey of patterns of care for brain-tumor patients

1 reference

12 December 2020

Antitumor activity of carcinoma-reactive BR96-doxorubicin conjugate against human carcinomas in athymic mice and rats and syngeneic rat carcinomas in immunocompetent rats.

1 reference

12 December 2020

Identification of the urokinase receptor as an adhesion receptor for vitronectin

1 reference

12 December 2020

Dosimetry and dose-response relationships in newly diagnosed patients with malignant gliomas treated with iodine-131-labeled anti-tenascin monoclonal antibody 81C6 therapy

1 reference

12 December 2020

Immunohistochemical localization of urokinase-type plasminogen activator, type-1 plasminogen-activator inhibitor, urokinase receptor and alpha(2)-macroglobulin receptor in human breast carcinomas

1 reference

12 December 2020

Malignant cerebral glioma--I: Survival, disability, and morbidity after radiotherapy.

1 reference

12 December 2020

Altered expression of epidermal growth factor receptor and estrogen receptor in MCF-7 cells after single and repeated radiation exposures

1 reference

12 December 2020

Relationship between antigen density and immunotherapeutic response elicited by monoclonal antibodies against solid tumors.

1 reference

12 December 2020

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1 reference

12 December 2020

The role of the diphtheria toxin receptor in cytosol translocation

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12 December 2020

Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy

1 reference

12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Recombinant Toxins for Cancer Treatment

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12 December 2020

Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms.

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12 December 2020

Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals

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12 December 2020

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion

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12 December 2020

The role of surgery in the management of supratentorial intermediate and high-grade astrocytomas in adults

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12 December 2020

Delivery of novel therapeutic agents in tumors: physiological barriers and strategies

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12 December 2020

Transport of molecules in the tumor interstitium: a review

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12 December 2020

Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis

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12 December 2020

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells.

1 reference

12 December 2020

Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.

1 reference

12 December 2020

Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1 reference

12 December 2020

Up-regulation of urokinase-type plasminogen activator and its receptor correlates with enhanced invasion activity of human glioma cells mediated by transforming growth factor-alpha or basic fibroblast growth factor

1 reference

12 December 2020

Potent and specific killing of human malignant brain tumor cells by an anti-transferrin receptor antibody-ricin immunotoxin.

1 reference

12 December 2020

1 reference

12 December 2020

Prognostic value of plasminogen activators and their inhibitors in colorectal cancer.

1 reference

12 December 2020

Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma

1 reference

12 December 2020

Antitumor activity of basic fibroblast growth factor-saporin mitotoxin in vitro and in vivo

1 reference

12 December 2020

Dose escalation with repeated intrathecal injections of 131I-labelled MAbs for the treatment of central nervous system malignancies

1 reference

12 December 2020

Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy

1 reference

12 December 2020

Pharmacokinetics and toxicology of immunotoxins administered into the subarachnoid space in nonhuman primates and rodents

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12 December 2020

Eradication of large solid tumors in mice with an immunotoxin directed against tumor vasculature

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12 December 2020

Redesigning nature's poisons to create anti-tumor reagents

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12 December 2020

Expression of oestrogen receptor and transforming growth factor-alpha in MCF-7 cells after exposure to fractionated irradiation

1 reference

12 December 2020

Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

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12 December 2020

The morbidity and mortality of brain tumors. A perspective on recent advances in therapy

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12 December 2020

1 reference

12 December 2020

Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice.

1 reference

12 December 2020

Pharmacokinetic considerations on monoclonal antibodies

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12 December 2020

Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates.

1 reference

12 December 2020

Increased expression of the epidermal growth factor receptor in human epidermal keratinocytes after exposure to ionizing radiation

1 reference

12 December 2020

Enhanced delivery improves the efficacy of a tumor-specific doxorubicin immunoconjugate in a human brain tumor xenograft model.

1 reference

12 December 2020

Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin.

1 reference

12 December 2020

Clinical trials of targeted toxins

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12 December 2020

Discrepancies in brain tumor extent as shown by computed tomography and positron emission tomography using [68Ga]EDTA, [11C]glucose, and [11C]methionine

1 reference

12 December 2020

Prognostic significance of the receptor for urokinase plasminogen activator in breast cancer

1 reference

12 December 2020

Brain metastases. Histology, multiplicity, surgery, and survival

1 reference

12 December 2020

A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes

1 reference

12 December 2020

Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas

1 reference

12 December 2020

A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells

1 reference

12 December 2020

Treatment of neuroectodermal brain tumors

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12 December 2020

Surgical treatment of multiple brain metastases

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12 December 2020

Topographic anatomy and CT correlations in the untreated glioblastoma multiforme.

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12 December 2020

Meningeal carcinomatosis

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12 December 2020

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

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12 December 2020

Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo.

1 reference

12 December 2020

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure

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12 December 2020

The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

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12 December 2020

Stereotactic radiosurgery for recurrent malignant gliomas

1 reference

12 December 2020

Enhancement of chemotherapy agents

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12 December 2020

Immunotoxins: a clinical review of their use in the treatment of malignancies

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12 December 2020

Targeted toxins as anticancer agents

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12 December 2020

The effect of immunotoxin against human glioma cells.

1 reference

12 December 2020

The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor

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12 December 2020

uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways?

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12 December 2020

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases

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12 December 2020

Pharmacokinetic analysis of the perivascular distribution of bifunctional antibodies and haptens: comparison with experimental data

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12 December 2020

A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells

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12 December 2020

Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.

1 reference

12 December 2020

Medulloblastoma: I. Clinical, diagnostic, and therapeutic overview

1 reference

12 December 2020

A randomized trial of surgery in the treatment of single metastases to the brain.

1 reference

12 December 2020

Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors

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12 December 2020

The pharmacology of monoclonal antibodies

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12 December 2020

In situ expression of interleukin-4 (IL-4) receptors in human brain tumors and cytotoxicity of a recombinant IL-4 cytotoxin in primary glioblastoma cell cultures

1 reference

12 December 2020

In Vitro and In Vivo Variation in Transferrin Receptor Expression on a Human Medulloblastoma Cell Line

1 reference

12 December 2020

A phase I study of an anti-epidermal growth factor receptor monoclonal antibody for the treatment of malignant gliomas

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1026238331739

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Dimensions Publication ID

9 August 2017

1040689513

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