(Q35603101)

English

RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.

scientific article published on 26 August 2011

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12 February 2020

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Europe PubMed Central

RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation (English)

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Europe PubMed Central

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12 February 2020

David A Schneider

1

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David Alan Schneider

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26 August 2011

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12 February 2020

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12 February 2020

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Europe PubMed Central

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12 February 2020

Promoter architectures in the yeast ribosomal expression program

1 reference

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27 July 2018

The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively

1 reference

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27 July 2018

Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

The multifunctional Ccr4-Not complex directly promotes transcription elongation

1 reference

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27 July 2018

Elongator protein 3b negatively regulates ribosomal DNA transcription in african trypanosomes

1 reference

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27 July 2018

Structural basis of RNA polymerase II backtracking, arrest and reactivation

1 reference

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27 July 2018

Reduction in ribosomal protein synthesis is sufficient to explain major effects on ribosome production after short-term TOR inactivation in Saccharomyces cerevisiae

1 reference

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27 July 2018

Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes

1 reference

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27 July 2018

Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription

1 reference

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27 July 2018

RNA polymerase I contains a TFIIF-related DNA-binding subcomplex

1 reference

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27 July 2018

TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production

1 reference

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27 July 2018

Yeast pre-rRNA processing and modification occur cotranscriptionally

1 reference

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27 July 2018

The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif

1 reference

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27 July 2018

The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer

1 reference

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27 July 2018

Structure-function analysis of RNA polymerases I and III.

1 reference

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27 July 2018

Driving ribosome assembly

1 reference

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27 July 2018

RNA polymerase II associated factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells

1 reference

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27 July 2018

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

1 reference

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27 July 2018

Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines

1 reference

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27 July 2018

The Paf1 complex is required for efficient transcription elongation by RNA polymerase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

UBF levels determine the number of active ribosomal RNA genes in mammals

1 reference

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27 July 2018

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

1 reference

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27 July 2018

RNA polymerases I and III, non-coding RNAs and cancer

1 reference

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27 July 2018

Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.

1 reference

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27 July 2018

Pseudo-NORs: a novel model for studying nucleoli

1 reference

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27 July 2018

Structure and function of ribosomal RNA gene chromatin

1 reference

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27 July 2018

Genome-wide location analysis reveals a role of TFIIS in RNA polymerase III transcription

1 reference

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27 July 2018

Functional architecture of RNA polymerase I

1 reference

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27 July 2018

Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription

1 reference

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27 July 2018

Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription

1 reference

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27 July 2018

Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly.

1 reference

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27 July 2018

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

1 reference

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27 July 2018

RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA.

1 reference

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27 July 2018

Nucleolin: a multiFACeTed protein.

1 reference

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27 July 2018

Nucleolin is required for RNA polymerase I transcription in vivo

1 reference

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27 July 2018

RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing

1 reference

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27 July 2018

UBF activates RNA polymerase I transcription by stimulating promoter escape.

1 reference

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27 July 2018

Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

Regulation of rRNA synthesis in human and mouse cells is not determined by changes in active gene count

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

Growth factor signaling regulates elongation of RNA polymerase I transcription in mammals via UBF phosphorylation and r-chromatin remodeling

1 reference

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27 July 2018

PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

27 July 2018

Histones are required for transcription of yeast rRNA genes by RNA polymerase I.

1 reference

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27 July 2018

The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis

1 reference

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27 July 2018

Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae

1 reference

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27 July 2018

The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo

1 reference

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27 July 2018

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

1 reference

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27 July 2018

The Paf1 complex has functions independent of actively transcribing RNA polymerase II.

1 reference

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27 July 2018

mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability

1 reference

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27 July 2018

mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.

1 reference

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27 July 2018

Tor Pathway Regulates Rrn3p-dependent Recruitment of Yeast RNA Polymerase I to the Promoter but Does Not Participate in Alteration of the Number of Active Genes

1 reference

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27 July 2018

FACT facilitates transcription-dependent nucleosome alteration

1 reference

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27 July 2018

ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.

1 reference

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27 July 2018

In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes

1 reference

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27 July 2018

Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins

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27 July 2018

Camptothecins: a review of their chemotherapeutic potential

2 references

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27 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

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27 July 2018

UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

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27 July 2018

Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.

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27 July 2018

NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines

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27 July 2018

Mechanism of transcription initiation and promoter escape by RNA polymerase II.

1 reference

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27 July 2018

Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1

1 reference

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27 July 2018

The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3

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27 July 2018

Control of elongation by RNA polymerase II

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27 July 2018

Repression of RNA polymerase I transcription by the tumor suppressor p53

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27 July 2018

TATA binding protein can stimulate core-directed transcription by yeast RNA polymerase I.

1 reference

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27 July 2018

Architecture of RNA polymerase II and implications for the transcription mechanism

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27 July 2018

RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human

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27 July 2018

The economics of ribosome biosynthesis in yeast

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27 July 2018

Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution.

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27 July 2018

Expansion and contraction of ribosomal DNA repeats in Saccharomyces cerevisiae: requirement of replication fork blocking (Fob1) protein and the role of RNA polymerase I

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27 July 2018

A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription

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27 July 2018

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

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27 July 2018

Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I

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27 July 2018

Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein

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27 July 2018

A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine

1 reference

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27 July 2018

RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression

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27 July 2018

The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

1 reference

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27 July 2018

RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I.

1 reference

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27 July 2018

Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae

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27 July 2018

Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle

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27 July 2018

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

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27 July 2018

SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae

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27 July 2018

Ultrastructural patterns of RNA synthesis during early embryogenesis of Drosophila melanogaster.

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27 July 2018

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

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25 September 2018

Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.

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25 September 2018

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Transcript Elongation by RNA Polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Abundance of ribosomal RNA gene copies maintains genome integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

FACT facilitates chromatin transcription by RNA polymerases I and III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Site specific phosphorylation of yeast RNA polymerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Identification of novel functional TBP-binding sites and general factor repertoires

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

The RNA polymerase I transcription machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Nucleolar size and activity are related to pRb and p53 status in human breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between RNA polymerase I and II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Transcription of protein-coding genes in trypanosomes by RNA polymerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Characterization and mutagenesis of the gene encoding the A49 subunit of RNA polymerase A in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3234310

25 September 2018

Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/21893173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of transcription through the nucleosome by eukaryotic RNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21893173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERK modulates DNA bending and enhancesome structure by phosphorylating HMG1-boxes 1 and 2 of the RNA polymerase I transcription factor UBF

1 reference

https://pubmed.ncbi.nlm.nih.gov/21893173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.GENE.2011.08.006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21893173%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21893173%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21893173%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

ResearchGate publication ID

0 references

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